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Intraosseous neurilemmoma of the mandible

机译:下颌骨骨内神经瘤

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摘要

Neurilemmomas are relatively uncommon lesions most commonly encountered in the nerve sheath originating from Schwann cells. They are rarely found in the oral cavity and are characterized by solitary occurrence, slow, persistent growth and smooth surface, along with inconsistent clinical aspects depending on the nerve origin. Microscopically, the lesion typically comprises of alternating regions of hypercellularity and hypocellularity such as Antoni A and Antoni B arrangements, respectively. Here, we present a case of a benign spindle cell tumor of the mandible reflecting a case of intraosseous neurilemmoma in a 33-year-old female patient. Immunopositivity with S-100 and vimentin clearly indicates the lesion to be a spindle cell tumor with neural involvement. The prognosis was favorable; complete surgical removal was the treatment of choice with no recurrence noted. The present case further magnifies the importance of neurilemmoma and further aids in the differential diagnosis of several other benign soft tissue tumors in the oral cavity.
机译:神经膜瘤是相对罕见的病变,最常见于源自雪旺细胞的神经鞘。它们很少在口腔中发现,其特征是单独发生,缓慢,持续的生长和光滑的表面,以及取决于神经起源的不一致的临床方面。在显微镜下,病变通常包括高细胞性和低细胞性的交替区域,例如分别为Antoni A和Antoni B排列。在这里,我们介绍了一例下颌骨良性纺锤体细胞瘤,反映了一名33岁女性患者的骨内神经鞘瘤。 S-100和波形蛋白的免疫阳性反应清楚地表明该病变为具有神经侵犯的梭形细胞肿瘤。预后良好。完全手术切除是不复发的首选治疗方法。本病例进一步放大了神经性乳腺瘤的重要性,并进一步有助于对口腔中其他几种良性软组织肿瘤的鉴别诊断。

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