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首页> 外文期刊>Journal of International Medical Research >Intraperitoneal Ropivacaine for Effective Pain Relief after Laparoscopic Appendectomy: A Prospective, Randomized, Double-blind, Placebo-controlled Study
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Intraperitoneal Ropivacaine for Effective Pain Relief after Laparoscopic Appendectomy: A Prospective, Randomized, Double-blind, Placebo-controlled Study

机译：腹腔罗哌卡因可有效缓解腹腔镜阑尾切除术后疼痛：一项前瞻性，随机，双盲，安慰剂对照研究

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This prospective, randomized, double-blind, placebo-controlled study evaluated the effectiveness of intraperitoneal instillation of ropivacaine in the relief of pain in patients undergoing laparoscopic appendectomy. Patients in group C (placebo control group; n = 33) received normal saline and those in group I (instillation group; n = 30) received an instillation of 2 mg/kg ropivacaine at the initiation of the pneumoperitoneum. Visual analogue scale pain scores, fentanyl consumption and the frequency at which patients pushed the button (FPB) of a patient-controlled analgesia system during the post-operative period were significantly lower in group I compared with group C, and decreased gradually with time in both groups. The total amount of fentanyl consumed and the total FPB were significantly lower in group I compared with group C. Thus, intraperitoneal ropivacaine instillation reduced pain during the post-operative period after laparoscopic appendectomy. In addition, this drug was easy to administer and had no adverse effects at the dose used.
机译：这项前瞻性，随机，双盲，安慰剂对照研究评估了罗哌卡因腹膜内滴注对腹腔镜阑尾切除术患者缓解疼痛的有效性。 C组（安慰剂对照组; n = 33）的患者接受生理盐水，I组（滴注组; n = 30）的患者在气腹开始时滴注2 mg / kg罗哌卡因。视觉模拟评分疼痛评分，芬太尼消耗量和术后自控镇痛系统按按钮（FPB）的频率在I组比C组显着降低，而在C组随着时间的推移逐渐降低两组。与C组相比，I组的芬太尼消耗总量和FPB总量均显着降低。因此，腹腔罗哌卡因滴注可减轻腹腔镜阑尾切除术后的疼痛。另外，该药物易于施用，并且在所用剂量下没有副作用。

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