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首页> 外文期刊>Journal of International Medical Research >Systemic Lupus Erythematosus and hearing disorders: Literature review and meta-analysis of clinical and temporal bone findings
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Systemic Lupus Erythematosus and hearing disorders: Literature review and meta-analysis of clinical and temporal bone findings

机译：系统性红斑狼疮和听力障碍：文献综述和临床和颞骨发现的荟萃分析

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Objective This literature review and meta-analysis was performed to evaluate the correlations among hearing and vestibular clinical symptoms, temporal bone findings, and pathological mechanisms in patients with systemic lupus erythematosus (SLE). Study design Relevant papers in the literature were retrospectively reviewed. Clinical hearing aspects in patients with SLE and relevant temporal bone studies in the same field were analyzed. Methods PubMed and Google Scholar searches were performed using the following keywords: “auto-immune disease,” “systemic lupus erythematosus (SLE),” “hearing loss,” “temporal bone study,” “vertigo,” “dizziness,” “tinnitus,” “ear symptoms,” “treatment,” “diagnosis,” “symptoms,” “etiopathogenesis,” “Wegener granulomatosis,” “Sjogren,” “polyarteritis nodosa,” “Cogan syndrome,” and “granulomatosis.” Also included were reviews in which the following terms were present: “SLE,” “temporal bone,” and “hearing symptoms.” Review and conclusion This literature review and meta-analysis focused on the pathological mechanisms through which SLE can damage inner ear structures and determinate hearing and vestibular symptoms. The main mechanisms involved in inner ear damage include the autoimmune response, deposition of immune complexes in the vessels and, to a lesser extent, cytotoxic damage.
机译：目的对系统性红斑狼疮（SLE）患者的听力和前庭临床症状，颞骨发现和病理机制之间的相关性进行文献综述和荟萃分析。研究设计回顾性回顾文献中的相关论文。分析了SLE患者的临床听力方面以及同一领域的相关颞骨研究。方法使用以下关键词进行PubMed和Google Scholar搜索：“自身免疫性疾病”，“系统性红斑狼疮（SLE）”，“听力丧失”，“颞骨研究”，“眩晕”，“头晕”，“耳鸣” ”，“耳朵症状”，“治疗”，“诊断”，“症状”，“病因”，“韦格纳肉芽肿病”，“舍格伦”，“结节性多发炎”，“科根综合症”和“肉芽肿病”。还包括其中出现以下术语的评论：“ SLE”，“颞骨”和“听力症状”。综述和结论这篇文献综述和荟萃分析的重点是SLE可以通过其损害内耳结构并确定听力和前庭症状的病理机制。内耳损伤所涉及的主要机制包括自身免疫反应，免疫复合物在血管中的沉积以及较小程度的细胞毒性损伤。

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