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首页> 外文期刊>Journal of Indian Society of Periodontology >Effect of scaling and root planing as monotherapy on glycemic control in patients of Type 2 diabetes with chronic periodontitis: A systematic review and meta-analysis
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Effect of scaling and root planing as monotherapy on glycemic control in patients of Type 2 diabetes with chronic periodontitis: A systematic review and meta-analysis

机译：刮治和根治术作为单一疗法对2型糖尿病慢性牙周炎患者血糖控制的影响：系统评价和荟萃分析

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Background: There is enough evidence, which suggests that nonsurgical periodontal therapy (NSPT) improved the glycemic control in patients of Type 2 diabetes mellitus (T2DM) with chronic periodontitis (CP). This meta-analysis is aimed to explore the effect of NSPT, exclusively scaling and root planing (SRP) as monotherapy on glycemic control and periodontal parameters in patients of T2DM with CP. Materials and Methods: Two databases, MEDLINE and EMBASE, were searched from June 2006 to June 2016. Initially, 464 potentially relevant studies were evaluated. Randomized controlled trials with duration of ≥3 months, based on the treatment group managed with SRP without any supportive use of local drug delivery or systemic antibiotics, while the control group received no periodontal therapy, were selected. This resulted in six appropriate articles with a total of 812 patients of T2DM with CP. Alteration in glycated hemoglobin (HbA1c) was the primary outcome measure, whereas the changes in clinical attachment level (CAL) and probing pocket depth (PPD) were the secondary outcome measures. Results: SRP treatment resulted in a decrease in HbA1c by 0.26% (P = 0.17) at 3–4 months compared to the control group. Further, on subgroup analysis, SRP therapy revealed a decrease in PPD and CAL at 3–4 months, though statistically insignificant. Conclusion: SRP treatment leads to modest improvement in glycemic status and periodontal parameters in T2DM patients with CP at 3–4 months.
机译：背景：有足够的证据表明，非手术性牙周治疗（NSPT）改善了2型糖尿病（T2DM）慢性牙周炎（CP）患者的血糖控制。这项荟萃分析旨在探讨NSPT（仅结垢和根部平整（SRP）作为单一疗法）对CP型T2DM患者的血糖控制和牙周参数的影响。材料和方法：2006年6月至2016年6月，检索了MEDLINE和EMBASE两个数据库。最初，对464项潜在相关研究进行了评估。选择不使用任何局部药物递送或全身性抗生素的SRP治疗的治疗组，为期≥3个月的随机对照试验，而对照组未接受牙周治疗。这产生了六篇合适的文章，总共812例CP的T2DM患者。糖化血红蛋白（HbA1c）的改变是主要的结局指标，而临床依从水平（CAL）和探查袋深度（PPD）的变化是次要结局指标。结果：与对照组相比，SRP治疗导致3-4个月HbA1c降低0.26％（P = 0.17）。此外，在亚组分析中，SRP治疗显示3-4个月时PPD和CAL降低，尽管在统计学上不显着。结论：SRP治疗可在3-4个月的CP T2DM患者中适度改善其血糖状况和牙周参数。

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