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首页> 外文期刊>Journal of International Medical Research >Pivmecillinam plus Pivampicillin in Complicated Urinary Tract Infection. Double-Blind Comparison of the Combination Pivmecillinam/Pivampicillin and Pivmecillinam Alone in Patients with Urinary Tract Infection
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Pivmecillinam plus Pivampicillin in Complicated Urinary Tract Infection. Double-Blind Comparison of the Combination Pivmecillinam/Pivampicillin and Pivmecillinam Alone in Patients with Urinary Tract Infection

机译：复杂性尿路感染中的吡维西那南加匹维西林。尿路感染患者中吡美西那/吡喃西林和吡美西那单独的双盲比较

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Twenty-six surgical-urological patients with severe underlying diseases of the urinary tract and an acute urinary tract infection received a 10-day treatment with either pivmecillinam, 400 mg three tmes daily (twelve patients), or the fixed dose combination of pivmecillinam/pivampicillin (pivmecillinam 200 mg plus pivampicillin 250 mg) three times daily (fourteen patients). Eleven of the fourteen patients given combined therapy were cured bacteriologically, compared to only four out of twelve patients taking pivmecillinam alone. Clinical success was achieved in eleven out of fourteen patients who received combination therapy and in seven out of twelve subjects given pivmecillinam. Mild gastro-intestinal discomfort was recorded in a few patients in both treatment groups. The results suggest that the combination of pivmecillinam and pivampicillin is a promising alternative in patients with complicated urinary tract infections.
机译：患有严重尿路潜在疾病和急性尿路感染的26例外科泌尿外科患者接受皮莫西南治疗，每天400 mg每天3 tmes的吡喹西南治疗10天（十二名患者），或固定剂量的吡喹西林/皮氨苄西林联合治疗（吡维西南200毫克加匹维西林250毫克）每天3次（十四名患者）。在接受联合治疗的14名患者中，有11名通过细菌学治愈，而仅接受吡维西南的12名患者中只有4名通过细菌学治愈。在接受联合疗法的十四名患者中，有十一名获得了临床成功，在接受吡维西米那治疗的十二名患者中，有七名获得了临床成功。两个治疗组中的几例患者均出现了轻度的胃肠不适。结果表明，在复杂性尿路感染患者中，吡维西南和吡喃西林的组合是有希望的替代方法。

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