...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of International Medical Research >Celestone? Phosphate Injection High Dose: Treatment of Septic Shock and Impending Transplant Rejection
【24h】

Celestone? Phosphate Injection High Dose: Treatment of Septic Shock and Impending Transplant Rejection

机译：Celestone？磷酸盐注射大剂量：败血性休克的治疗和即将发生的移植排斥

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Celestone? Phosphate Injection was administered as an intravenous bolus to twenty patients, eighteen with septic shock and two with impending acute renal transplant rejection. Within 4 hours following the diagnosis of septic shock, adjunctive corticosteroid therapy in a dosage ranging from 2·88–3·11 mg/kg was given every 4 hours. The two patients with impending acute renal transplant rejection were dosed every 24 hours. Intravenous fluids, ventilatory assistance, antimicrobial agents, vasoactive agents, diuretics, digitalis and antipyretics were among the concomitant therapies. Among measurements monitored during the study, vital signs, arterial blood gases, central venous pressure, complete blood count, blood chemistry, electrocardiograms and chest radiographs indicated improvement in each patient's condition by the end of therapy. Rapid clinical improvement occurred within 4–8 hours for patients with septic shock and within 48 hours for patients with kidney transplants. Two to three doses of medication were required. Complete reversal of shock was achieved in eighteen (100%) patients with septic shock; both (100%) renal transplant patients experienced reversal of impending rejection. Tolerance was good and no adverse experiences were reported.
机译：Celestone？磷酸盐注射液以静脉推注的方式给予20例患者，其中18例患有败血性休克，2例即将发生急性肾移植排斥反应。在诊断为败血性休克后的4个小时内，每4个小时进行一次辅助皮质激素治疗，剂量为2·88-3·11 mg / kg。每24小时对两名即将发生急性肾移植排斥反应的患者进行给药。伴随疗法包括静脉输液，通气辅助，抗菌剂，血管活性剂，利尿剂，洋地黄和退热剂。在研究期间监测的测量结果中，生命体征，动脉血气，中心静脉压，全血细胞计数，血液化学，心电图和胸部X线照片表明，治疗结束后每位患者的病情均得到改善。败血性休克患者在4-8小时内以及肾移植患者在48小时内发生了快速的临床改善。需要两到三剂药物。十八名（100％）败血性休克患者完全恢复了休克。两名（100％）肾移植患者均经历了即将发生的排斥反应的逆转。耐受性良好，没有不良反应的报道。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号