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首页> 外文期刊>Journal of International Medical Research >Serum levels of IL-6, IL-8, and IL-10 are indicators of prognosis in pancreatic cancer
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Serum levels of IL-6, IL-8, and IL-10 are indicators of prognosis in pancreatic cancer

机译：血清IL-6，IL-8和IL-10水平是胰腺癌预后的指标

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Objective Early detection and prognosis prediction are critical to improve patient survival in pancreatic cancer. This study aimed to investigate whether interleukins could serve as indicators of prognosis in pancreatic cancer. Methods Sixty-eight patients with pancreatic cancer were enrolled in the study during the period between 2012 and 2014. The serum levels of a broad spectrum of interleukins in these patients were determined, including IL-1β, IL-2, IL-6, IL-8, IL-10, IL-13, IL-15, and IL-23. Results IL-6, IL-8, and IL-10 showed significant positive correlations with each other. Moreover, high levels of serum IL-6, IL-8, and IL-10 were independently strongly associated with poor survival of patients with pancreatic cancer. Conclusions Our results suggest that serum levels of IL-6, IL-8, and IL-10 could be useful markers for prediction of prognosis in patients with pancreatic cancer.
机译：目的早期发现和预后预测对于提高胰腺癌患者的生存至关重要。这项研究旨在调查白介素是否可以作为胰腺癌预后的指标。方法选择2012年至2014年间的68例胰腺癌患者作为研究对象，对这些患者的血清白介素水平进行测定，包括IL-1β，IL-2，IL-6，IL。 -8，IL-10，IL-13，IL-15和IL-23。结果IL-6，IL-8和IL-10相互之间呈显着正相关。此外，血清IL-6，IL-8和IL-10的高水平独立地与胰腺癌患者的不良生存密切相关。结论我们的结果表明，血清IL-6，IL-8和IL-10的水平可能是预测胰腺癌患者预后的有用标志物。

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