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Modelling aldehyde oxidase activity in aqueous-organic solvent mixtures at various temperatures

机译:在各种温度下模拟水性有机溶剂混合物中的醛氧化酶活性

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摘要

A model is proposed to represent the enzyme activity ratios in water – organic solvent mixtures at various temperatures. The prediction capability of the model was evaluated employing aldehyde oxidase as a model enzyme in seven water – organic solvent mixtures at 25, 35 and 45 °C by using mean percentage deviation (MPD). The MPD obtained for each water – organic solvent mixture was 6.2%. A general model was also proposed employing the Abraham solvent parameters with MPD as 19.5%. The proposed models could be used in industry for speeding up the process designs where water – organic solvent mixtures at various temperatures were employed.
机译:提出了一个模型来代表不同温度下水-有机溶剂混合物中酶的活性比。使用醛氧化酶作为模型酶,在25、35和45°C下的七种水-有机溶剂混合物中,使用平均百分比偏差(MPD)评估了模型的预测能力。每种水与有机溶剂的混合物所获得的MPD为6.2%。还提出了使用Abraham溶剂参数和MPD为19.5%的通用模型。建议的模型可用于工业中,以加快采用各种温度下的水-有机溶剂混合物的工艺设计。

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