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首页> 外文期刊>Journal of medical bacteriology. >Lactobacillus rhamnosus Gorbach-Goldin (GG): A Top Well-Researched Probiotic Strain
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Lactobacillus rhamnosus Gorbach-Goldin (GG): A Top Well-Researched Probiotic Strain

机译：鼠李糖乳杆菌戈尔巴赫-戈尔丁（GG）：顶级的益生菌菌株

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Probiotics, living microorganisms which when used in adequate amounts, have health bene?ts on the host, have attracted a considerable deal of interest in the biotechnology market. Various prokaryotic and eukaryotic microbes have been studied for probiotic purposes in human and animals. Lactobacillus and Bifidobacterium are the main probiotic genera; however, there are reports on the probiotic potential of strains belonging to Bacillus, Lactococcus, Pediococcus and also some yeast species. Lactobacillus species are regarded as the most investigated beneficial microbes for human and either animal probiotic development due to: a) anti-inflammatory effects, b) anti-allergic features, c) secretion of antimicrobial compounds, d) develops in aerobic and anaerobic conditions, and e) many Lactobacilli have been Generally Recognized As Safe (GRAS) by the Food and Drug Administration (FDA). Among Lactobacilli, Lactobacillus rhamnosus Gorbach-Goldin (GG) is known among the most in-detail studied strains and is regarded as a top well-researched and commercialized probiotic strain in the industrial biotechnology. Strain GG is a commercially significant probiotic which was originally isolated from the healthy human gastrointestinal tract in 1983. The documents studied this strain were reviewed here and it is shown that such successful strains in the probiotic market have been extensively studied from the probiotic traits and safety point of views and a minor part of the documents concerned the bioprocessing issues. Also, we showed that the beneficial and negative effects of this strain has been investigated in various clinical trial systems when it became commercialized. Various aspects of this strain are here reviewed, comparatively.
机译：益生菌是一种生活中的微生物，当适量使用时，会对宿主产生健康益处，因此在生物技术市场上引起了相当大的兴趣。为了人类和动物中的益生菌目的，已经研究了各种原核和真核微生物。乳酸杆菌和双歧杆菌是主要的益生菌属。然而，有报道说，属于芽孢杆菌，乳球菌，Pediococcus和某些酵母菌的菌株具有益生菌的潜力。乳酸杆菌物种被认为是对人类和动物益生菌发育研究最多的有益微生物，原因是：a）抗炎作用，b）抗过敏特性，c）抗菌化合物的分泌，d）在有氧和厌氧条件下发展， e）许多乳杆菌已被食品和药物管理局（FDA）普遍认可为安全（GRAS）。在乳酸杆菌中，鼠李糖乳杆菌戈尔巴赫-戈尔丁（GG）被认为是研究最深入的菌株之一，被认为是工业生物技术中研究和商业化程度最高的益生菌菌株。 GG菌株是一种商业上重要的益生菌，最初于1983年从健康的人胃肠道中分离出来。此处对有关该菌株的研究文献进行了综述，结果表明，从益生菌的性状和安全性出发，对这种成功的菌株在益生菌市场进行了广泛研究。观点和文件的一小部分涉及生物加工问题。同样，我们表明，该菌株商品化后，已经在各种临床试验系统中对其进行了有益和不利的研究。对此菌株的各个方面进行了比较回顾。

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