Anti-stress Activity of Mitragyna africanus (Willd), Stembark Extract

B. M. Aji; K. D. Effraim; P. A. Onyeyili

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Anti-stress Activity of Mitragyna africanus (Willd), Stembark Extract

机译：非洲藜（Willd），树干提取物的抗应激活性

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The acute toxicity and the effect of Mitragyna africanus stembark extract of methanol (CH₃OH) on stress were investigated in rats, using its effect on pentyleneterazole induced convulsions and its muscle relaxant effect. The extract did not produce any death in the treated rats even at the highest dose (6400mg kg-1) used. It did not protect rats treated with convulsive doses of pentylenetetrazol (100mg kg-1) but increased the period of onset of convulsions and decreased the number of spasms. It also showed significant (p<0.05) muscle relaxant effect

机译：考察了非洲三叶草甲醇提取物（CH _{3 OH）对大鼠的急性毒性和对应激的影响，利用其对戊烯二唑诱发的惊厥的作用及其肌肉松弛作用。即使使用最高剂量（6400mg kg -1 ），提取物也不会在治疗的大鼠中引起任何死亡。它不能保护惊厥剂量戊四唑（100mg kg -1 ）治疗的大鼠，但会增加惊厥发作的时间并减少痉挛的次数。它还显示出显着的（p <0.05）肌肉松弛作用}

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《Journal of Medical Sciences》 |2001年第3期|共3页
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B. M. Aji; K. D. Effraim; P. A. Onyeyili;
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中图分类医药、卫生;
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2. Lack of toxicity of hydroethanolic extract from Mitragyna inermis (Willd.) O. Kuntze by gavage in the rat. [J] . Monjanel Mouterde S, Traore F, Gasquet M, Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2006,第3期

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5. Analytical methodology for the quantitation of mitragynine and the fingerprinting of crude extracts of Mitragyna speciosa. [D] . Adkins, Jessica Erin. 2008

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6. Antimicrobial Activities of Hexane Extract and Decussatin from Stembark Extract of Ficus congensis [O] . Chinwendum Stephenie Alaribe, Francis Shode, Herbert A. B. Coker, 2011

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7. Anti-stress Activity of Mitragyna africanus (Willd), Stembark Extract [O] . B. M. Aji, K. D. Effraim, P. A. Onyeyili 2001

机译：mitragyna africanus（Willd），stembark Extract的抗应激活性

Anti-stress Activity of Mitragyna africanus (Willd), Stembark Extract

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