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High-Level Vancomycin-Resistant Staphylococcus aureus (VRSA) in Iran: A Systematic Review

机译:伊朗的高耐万古霉素金黄色葡萄球菌(VRSA):系统评价

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Background: Staphylococcus aureus is a major human pathogen world wide. Vancomycin has been used for decades to treat multidrug resistant S. aureus. Ten years has passed since the first report of vancomycin re sistant S. aureus (VRSA). The objective of this systematic review was to determine the total number of VRSA isolates that have been reported from Iran.Methods: Search terms reflected “Iran”, “vancomycin” and “S. aureus” were searched in the ISI web of knowledge, PubMed, SciVerse, and Google scholar. Also two Persian scientific databases and 13 recent na tional congresses were investigated. Articles / abstracts working on S. aureus in Iran, evaluating vancomycin MIC and / or PCR of vanA/B were included in this systematic review.Results: Out of the 3484 records found in mentioned resources, 13 related studies were included in the final analysis. The result showed that at least 24 VRSA isolates which have been reported from Iran up to September 2012.Conclusion: It seems that many Iranian researchers did not follow a spe cific guideline for reporting and confirming VRSA. Establishing an Iranian reference center where studies on VRSA can be registered, evaluated and confirmed is strongly recommended.
机译:背景:金黄色葡萄球菌是全世界主要的人类病原体。万古霉素已经用于治疗耐多药金黄色葡萄球菌。自第一份耐万古霉素金黄色葡萄球菌(VRSA)报道以来已经过去了十年。这项系统审查的目的是确定已从伊朗报告的VRSA分离株总数。方法:检索词反映“伊朗”,“万古霉素”和“ S.”。在ISI知识网,PubMed,SciVerse和Google Scholar中搜索了“金黄色葡萄球菌”。还调查了两个波斯科学数据库和最近的13个全国代表大会。该系统评价包括文章/摘要,涉及伊朗金黄色葡萄球菌,评估万古霉素MIC和/或vanA / B的PCR。结果:在上述资源中发现的3484条记录中,有13项相关研究被纳入最终分析。结果表明,截至2012年9月,伊朗至少报告了24种VRSA分离株。结论:似乎许多伊朗研究人员并未遵循特定的指导方针来报告和确认VRSA。强烈建议建立一个伊朗参考中心,以注册,评估和确认有关VRSA的研究。

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