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首页> 外文期刊>Journal of medical bacteriology. >Incidence of Recurrent Urinary Tract Infection after Renal Transplantation
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Incidence of Recurrent Urinary Tract Infection after Renal Transplantation

机译：肾移植术后复发性尿路感染的发生率

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Background: The pathologies classified as urinary tract infections (UTI) can have a deleterious effect on patients who have undergone a renal transplantation. Often recurrent UTIs will occur, leading to high morbidity, failure of the grafting process overall and even death. The study presented here seeks to expand the knowledge of recurrent UTIs in the context of renal transplantation, what risks recurrent UTIs pose to transplant patients and evaluate possible treatments.Methods: Renal transplantations were performed on 94 patients. For six months post-surgery the patients were evaluated for the presence of recurrent UTIs. The criteria for determining a patient as having a UTI was given as finding more than 103 and 105 pure colonies within one ml of urine for asymptomatic and symptomatic patients, respectively. The criteria of recurrent UTI was defined as two or more conclusive UTIs within the first six months after the surgery or three more within a year after renal transplantation.Results: Of the 94 hospitalized patients, 29 UTIs were diagnosed (30.8%). The majority of diagnosed UTIs were in female patients (11.15, 73.3% vs.4.15, 26.7%; p-value = 0.003). Those patients with diabetes mellitus correlated with a better chance of having a UTI (p-value = 0.019; CI = 1.2-12.2). The incidence rate of UTI was 51.7%, female predominant 73.3%. No other pathologies were shown to affect the chance of developing recurrent UTIs. Typically Escherichia coli was the bacterium isolated from urine cultures (48.3%) from those who developed recurrent UTI. The isolates tended to possess resistance to TMP / SMX and piperacillin but were susceptible to imipenem.Conclusion: Recurrent UTIs in renal transplant patients can be mitigated with proper identification of risk factors.
机译：背景：分类为尿路感染（UTI）的病理可能会对接受肾移植的患者产生有害影响。经常发生复发性尿路感染，导致高发病率，整个移植过程失败甚至死亡。本研究旨在扩大肾脏移植背景下复发性UTI的知识，复发性UTI给移植患者带来的风险并评估可能的治疗方法。方法：对94例患者进行了肾脏移植。术后六个月，评估患者是否存在复发性UTI。确定无尿路感染患者的标准是，在无症状和有症状的患者的一毫升尿液中分别发现103个和105个以上的纯菌落。复发性尿路感染的标准被定义为在手术后的前六个月内有两个或更多的决定性尿路感染，或在肾移植后一年内的三个以上。结果：在94例住院患者中，诊断出29例尿路感染（30.8％）。诊断出的大多数UTI是女性患者（11.15，73.3％vs.4.15，26.7％; p值= 0.003）。那些患有糖尿病的患者与尿路感染的机会更高（p值= 0.019; CI = 1.2-12.2）。尿路感染的发生率为51.7％，女性占73.3％。没有其他病理显示影响复发性UTI的机会。通常，大肠杆菌是从尿液培养物中分离出的细菌（48.3％），这些细菌是从那些复发性UTI患者身上分离出来的。分离株倾向于对TMP / SMX和哌拉西林具有抗药性，但对亚胺培南敏感。结论：适当识别危险因素可以减轻肾移植患者复发性UTI。

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