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Investigating Colonization of Staphylococcus aureus among Patients Admitted to the Infectious Diseases Ward of Imam Hospital in Mashhad

机译:在马什哈德伊玛目医院传染病病房住院的金黄色葡萄球菌定植调查

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Introduction: Staphylococcus aureus colonization has been recognized as one of the most important risk factors for subsequent infections with this microorganism. In this study, we intended to identify all patients who were MRSA-positive upon admission and compare the prevalence of MRSAcolonization on different days of study admitted in Imam Reza hospital in Mashhad, Iran.Methods: This cross-sectional study was done on 600 admitted patients in Infectious disease ward. Samples of patients were drawn from patients’ nares (and if they were culture negative, re-cultures were done on days 3, 7 and finally on discharge time. After identification of the isolates, theirsusceptibility to methicillin was evaluated. Before we collect nasal swabs, patients filled out a survey questionnaire.Results: S. aureus colonization early after hospitalization in infectious ward was observed in 39.8% (n=239) of patients, of which 59% (n=141) were resistant to methicillin. On the third day of admission, S. aureus new colonization rate was 15.8% (n=57), of which 87.7% (n=50) were methicillin resistant. On the seventh day, S. aureus were found in 13% (n=32) patients with 90.6% (n=29) were methicillin-resistant. Upon discharge, 8.2% (n=13) patients were S. aureus positive and 92.3% (n=12) were resistant to methicillin.Conclusion: Most of the carriers had the methicillin resistant strains of bacteria at the time of admission, and the number of colonized patients with resistant bacteria increased in time. The most common risk factors in methicillin-resistant S. aureus carriers were taking antibiotic, history of priorhospitalization and being an intravenous (IV) drug abuser.
机译:简介:金黄色葡萄球菌定植已被认为是随后感染该微生物的最重要风险因素之一。在这项研究中,我们旨在确定所有入院时MRSA阳性的患者,并比较伊朗Mashhad的Imam Reza医院入院的不同研究日MRSA克隆化的发生率。方法:本横断面研究在600例入院患者中进行患者在传染病病房。从患者鼻孔中抽取患者样本(如果培养阴性,则在第3、7天,最后在出院时进行再培养。鉴定出分离物后,评估其对甲氧西林的敏感性。在收集鼻拭子之前结果:住院后感染病房早期金黄色葡萄球菌定植的比例为39.8%(n = 239),其中59%(n = 141)对甲氧西林有抗药性。入院当天,金黄色葡萄球菌的新定植率为15.8%(n = 57),其中87.7%(n = 50)耐甲氧西林;到第七天,发现金黄色葡萄球菌的新定植率为13%(n = 32)。 90.6%(n = 29)的患者对甲氧西林耐药;出院时,金黄色葡萄球菌阳性的患者为8.2%(n = 13),对甲氧西林的耐药率为92.3%(n = 12)。入院时耐甲氧西林的细菌菌株,以及耐药菌的定植人数细菌随时间增加。耐甲氧西林的金黄色葡萄球菌携带者中最常见的危险因素是服用抗生素,住院治疗史和静脉(IV)药物滥用者。

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