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首页> 外文期刊>Journal of medical bacteriology. >Prevalence and Antimicrobial Susceptibility of Staphylococcus aureus Isolated from Nasal Carriers
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Prevalence and Antimicrobial Susceptibility of Staphylococcus aureus Isolated from Nasal Carriers

机译：鼻载体分离的金黄色葡萄球菌的患病率和药敏性

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Background: Staphylococcus aureus (S. aureus) is one of the major virulence factors of hospital and community acquired infections. Healthcare workers can be the host of S.aureus for many months. And it is very important due to the possibility of transmission to patients. Theaim of this study was to determine the prevalence of S.aureus nasal carriers, the antibiotic susceptibility pattern and its effective factors on Sina Hospital workers in Tehran, Iran.Methods: healthcare workers from different wards of Sina Hospital were studied in Tehran, Iran in 2010. Samples were taken from both nostrils of each individual. After 18-24hr incubation, the isolates were evaluated by gram stain, catalase, coagulase, DNase and manitol salt agar bywhich staphylococci were isolated. Disk diffusion antimicrobial susceptibility tests against oxacillin, cefoxitin and vancomycin was performed. Finally, by using PCR, the mecA gene was studied in methicillin-resistant strains (MRSA).Results: 34of the 166 workers, were nasal carriers of S. aureus and one of them was MRSA. The ratio of carriers in operating room workers was more than other wards, without significant relationship (p.value>0.05). S.aureus was found in 34.3% of operating room, 13.8% of nurses and 22.7% of licensed and other personnel. There was a significant relationship betweenoccupations and S.aureus carriage (p.value:0.03).Conclusion: According to the low prevalence of S. aureus and MRSA carriers in Sina hospital, it can be said that the role of the hospital staff as a source of infections caused by S. aureus especially is very low.
机译：背景：金黄色葡萄球菌（S. aureus）是医院和社区获得性感染的主要毒力因子之一。医护人员可以担任金黄色葡萄球菌很多个月的宿主。由于可能传播给患者，因此非常重要。这项研究的目的是确定伊朗德黑兰的新浪医院工作人员的金黄色葡萄球菌鼻携带者的流行情况，抗生素敏感性模式及其影响因素。方法：在伊朗德黑兰对新浪医院不同病房的医护人员进行了研究。 2010年。样本取自每个人的两个鼻孔。温育18-24小时后，通过革兰氏染色，过氧化氢酶，凝固酶，DNase和甘露醇盐琼脂评估分离物，从而分离出葡萄球菌。进行了针对奥沙西林，头孢西丁和万古霉素的纸片扩散抗药性试验。最后，通过PCR技术，在耐甲氧西林菌株（MRSA）中研究了mecA基因。结果：166名工人中有34名是金黄色葡萄球菌的鼻携带者，其中之一是MRSA。手术室工作人员中携带者的比例高于其他病房，无显着相关性（p.value> 0.05）。在手术室的34.3％，护士的13.8％和执照及其他人员的22.7％中发现金黄色葡萄球菌。结论：由于金黄色葡萄球菌和MRSA携带者在新浪医院的患病率较低，可以说医院工作人员作为金黄色葡萄球菌的携带者与人之间有着显着的关系（p.value：0.03）。特别是金黄色葡萄球菌引起的感染源非常低。

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