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首页> 外文期刊>Journal of Medical Case Reports >Inflammatory pseudotumors of the kidney and the lung presenting as immunoglobulin G4-related disease: a case report
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Inflammatory pseudotumors of the kidney and the lung presenting as immunoglobulin G4-related disease: a case report

机译：表现为免疫球蛋白G4相关疾病的肾脏和肺部炎症性假瘤：病例报告

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Introduction It has been reported that immunoglobulin G4-related systemic disease can spread to nearly every organ, and often presents as an inflammatory mass or masses at those sites. In the kidney, this disease is often diagnosed after a radical or partial nephrectomy following the discovery of an inflammatory mass which is often suspected to be a malignant tumor. Here, we present a rare case of inflammatory pseudotumors of the kidney and the lung presenting as immunoglobulin G4-related disease, which were diagnosed by computed tomography-guided biopsies. Case presentation A 54-year-old Japanese man was referred to our hospital with suspected bilateral renal cancer, multiple lung metastases and autoimmune pancreatitis. His serum immunoglobulin G4 level was high. We used computed tomography-guided biopsies and histopathological examinations of the biopsied specimens to diagnose the tumors as immunoglobulin G4-related bilateral renal and lung inflammatory pseudotumors. Our patient was treated with oral prednisolone, and after one month of treatment, contrast-enhanced computed tomography demonstrated a general improvement, as noted by a reduction in size of the masses. Conclusion Renal masses that are formed due to immunoglobulin G4-related disease require comprehensive diagnosis to prevent unnecessary surgical resections from being performed. Further consideration should be paid to immunoglobulin G4-related diseases in the future.
机译：引言据报道，与免疫球蛋白G4相关的全身性疾病可扩散到几乎每个器官，并且通常在这些部位呈炎性肿块。在肾脏中，通常在发现炎症性肿块（通常被怀疑是恶性肿瘤）之后，在进行彻底或部分肾切除术后诊断出该疾病。在这里，我们介绍了一种罕见的肾脏和肺部炎性假瘤，表现为免疫球蛋白G4相关疾病，由计算机断层扫描引导的活检诊断。病例介绍一名54岁的日本男子因怀疑双侧肾癌，多发性肺转移和自身免疫性胰腺炎被转诊到我院。他的血清免疫球蛋白G4水平很高。我们使用计算机断层扫描引导的活检和活检标本的组织病理学检查，将肿瘤诊断为免疫球蛋白G4相关性双侧肾和肺炎性假瘤。我们的患者接受了口服泼尼松龙的治疗，经过一个月的治疗，对比增强的计算机断层扫描显示出总体的改善，这表明肿块的减小。结论因免疫球蛋白G4相关疾病而形成的肾脏肿块需要综合诊断，以防止进行不必要的手术切除。将来应进一步考虑免疫球蛋白G4相关疾病。

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