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首页> 外文期刊>Journal of Medical Sciences >The Antimicrobial Activity of Jatropha multifida Extracts and Chromatographic Fractions Against Sexually Transmitted Infections
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The Antimicrobial Activity of Jatropha multifida Extracts and Chromatographic Fractions Against Sexually Transmitted Infections

机译：麻风树提取物和色谱级分对性传播感染的抗菌活性

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摘要

This study was carried out to investigate the antimicrobial activity of the plant against different microorganisms especially those responsible for sexually transmitted infections which is becoming endemic in Africa. Hexane, ethyl acetate and methanol extracts of the plant and chromatographic fractions were screened against seven pathogenic organisms comprising gram positive and gram negative bacteria and fungi. The extracts and fractions displayed potent antimicrobial activity against these organisms, giving Minimum Inhibitory Concentrations (MIC) ranging from 0.75 to 12.5 μg mL-1 for the fractions. The results suggest that extracts of J. multifida could be used in treating sexually transmitted bacterial infections. Phytochemical screening of the extracts also showed the presence of steroids, alkaloids, saponins, tannins and glycosides.
机译：进行这项研究以研究植物对不同微生物的抗微生物活性，特别是对负责性传播感染的微生物的抗微生物活性，这种感染在非洲正在流行。针对包括革兰氏阳性和革兰氏阴性细菌和真菌在内的七种病原生物筛选了该植物的己烷，乙酸乙酯和甲醇提取物以及色谱级分。提取物和级分显示出对这些生物体的有效抗菌活性，级分的最低抑菌浓度（MIC）为0.75至12.5μgmL -1 。结果表明，多重假丝酵母的提取物可用于治疗性传播细菌感染。提取物的植物化学筛选还显示存在类固醇，生物碱，皂角苷，单宁和糖苷。

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