• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Medical Sciences >Comparative Lead-removing Activity of the Non-starch Polysaccharides
【24h】

Comparative Lead-removing Activity of the Non-starch Polysaccharides

机译：非淀粉多糖的除铅活性比较

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Lead is a ubiquitous environmental pollutant that poses a serious threat to human health. Therefore effective methods diminishing negative influence of this metal are of great importance. In this study lead binding activity of such non-starch polysaccharides as high and low esterified pectin, calcium alginate and lignin as well as of activated charcoal was estimated under in vitro and in vivo conditions. The adsorption of lead ions from aqueous solution by mentioned substances was studied in a batch sorption system. The lead-binding capacity of all polysaccharide compounds was highest within the pH range 4.0-8.0. The Langmuir and Freundlich sorption models were applied to describe the isotherms and sorption constants. Interactions between non-starch polysaccharides except lignin could be well interpreted by the Langmuir model. In experiments estimating lead removal from inner organs and femur in rats preliminary given the heavy metal solution for three weeks, calcium alginate and low esterified pectin were the most effective agents studied compared with others. They contributed to reduced lead concentration in organs and femur as well as increased metal content in feces of laboratory animals. The results suggest that low esterified pectin and calcium alginate may be considered perspective compounds purposed for prevention and treatment of chronic lead poisoning.
机译：铅是一种普遍存在的环境污染物，对人类健康构成严重威胁。因此，减少这种金属的负面影响的有效方法非常重要。在这项研究中，在体外和体内条件下，估计了高淀粉酯化果胶和低酯化果胶，藻酸钙和木质素等非淀粉多糖以及活性炭的铅结合活性。在间歇式吸附系统中研究了上述物质对水溶液中铅离子的吸附。在4.0-8.0的pH范围内，所有多糖化合物的铅结合能力最高。用Langmuir和Freundlich吸附模型描述等温线和吸附常数。 Langmuir模型可以很好地解释除木质素以外的非淀粉多糖之间的相互作用。在初步估计给定重金属溶液三周的大鼠中，从内脏和股骨中去除铅的实验中，藻酸钙和低酯化果胶比其他化合物是最有效的研究药物。它们有助于降低器官和股骨中的铅浓度，以及增加实验动物粪便中的金属含量。结果表明，低酯化果胶和海藻酸钙可能被认为是旨在预防和治疗慢性铅中毒的透视化合物。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号