Morphological Evidence of Apoptosis in Hepatocytes of Rats ( Rattus norvegicus ) Exposed to Arabian Incense

Saud A. Alarifi

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Morphological Evidence of Apoptosis in Hepatocytes of Rats ( Rattus norvegicus ) Exposed to Arabian Incense

机译：阿拉伯香染鼠（Rattus norvegicus）肝细胞凋亡的形态学证据。

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Hepatocytes of rat exposed to Arabian incense revealed morphological evidence of apoptosis in their nuclei. Irregularity of the nuclear membrane was probably the initial morphological alteration. Evident chromatin condensation was the following nuclear change. Nuclear fragmentation was the subsequent nuclear apoptotic change. Each nuclear fragment was delimited with intact membrane. No evidence of chromatin lysis was noticed in the altered nuclei. Markedly shrunken nuclei with condensed chromatin were also discerned. Cytoplasmic organelles of hepatocytes with apoptotic nuclei revealed no sign of deterioration. Kupffer cells in the vicinity of the apoptotic nuclei were hypertrophied and proliferated.

机译：暴露于阿拉伯香气的大鼠肝细胞揭示了其细胞核中凋亡的形态学证据。核膜的不规则性可能是最初的形态学改变。染色质的明显凝结是随后的核变化。核分裂是随后的核凋亡变化。每个核片段都用完整的膜定界。在改变的细胞核中没有发现染色质溶解的证据。还观察到明显浓缩的染色质收缩的细胞核。具有凋亡核的肝细胞的细胞质细胞器没有显示出恶化的迹象。凋亡核附近的库普弗细胞被肥大并增殖。

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《Journal of Medical Sciences》 |2005年第3期|共6页
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Saud A. Alarifi;
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中图分类医药、卫生;
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Morphological Evidence of Apoptosis in Hepatocytes of Rats ( Rattus norvegicus ) Exposed to Arabian Incense

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