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首页> 外文期刊>Journal of Molecular Biology Research >Evaluation of Clinical Symptoms Related to Common Serogroups of Leptospirosis in North of Iran
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Evaluation of Clinical Symptoms Related to Common Serogroups of Leptospirosis in North of Iran

机译：伊朗北部钩端螺旋体病常见血清群相关临床症状的评估

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Leptospirosis is a common disease between humans and animals. Identifying common serogroups and comparing different clinical symptoms among them can help in finding the clinical pattern associated with pathogen serogroupes of leptospirosis. Therefore, the purpose of this study has been to investigate the common serotypes of the infection and their clinical symptoms in northern Iran. This cross-sectional study was carried out in educational hospitals of Babol University of Medical Sciences during the years 2011- 2014. Subjects with clinical findings consistent with leptospirosis were included in the study. According to the standard MAT guidelines, the titre >=1: 200 was considered positive. Then, the patients identified by serogroup separation, were examined and compared clinical symptoms. Among 6o patients with primary diagnosis of leptospirosis in this study, 35 of them proved to be infected to the disease. The most common serogroups were serjoe (40%) and icterohemorrhagia (31.4%). Autumnalis (22.8%), grippotyphosa (11.4%), canicola (8.6%), and pomona (2.8%) were included the subsequent serogroups. The highest frequency of fever (28%) and gastrointestinal manifestations (36%) were observed in icterohemorrhagia and the highest icterus (30%) was found in serjoe serogroup. In this study, serjoe serogroup with fever and icterus, and then icterohemorrhagia with fever and gastrointestinal symptoms were introduced as the most common serogroups of Leptospirosis. Also the rarest serogroups were canicola and pomona.
机译：钩端螺旋体病是人与动物之间的常见疾病。识别常见血清群并比较它们之间的不同临床症状可以帮助找到与钩端螺旋体病病原体血清群相关的临床模式。因此，本研究的目的是调查伊朗北部常见的感染血清型及其临床症状。这项横断面研究是在2011-2014年间在巴博尔医科大学的教育医院进行的。该研究包括临床表现与钩端螺旋体病相符的受试者。根据标准MAT指南，滴度> = 1：200被认为是阳性。然后，对通过血清组分离鉴定出的患者进行检查并比较其临床症状。在这项研究中，最初诊断为钩端螺旋体病的6o位患者中，有35位被证明感染了该病。最常见的血清群是serjoe（40％）和黄疸性出血（31.4％）。秋季血清型（22.8％），腐烂症（11.4％），canicola（8.6％）和波莫纳（2.8％）包括在随后的血清群中。黄疸出血的发烧频率最高（28％），胃肠道表现最高（36％），而serjoe血清群中黄疸最高（30％）。在这项研究中，引入发烧和黄疸的serjoe血清群，然后发烧和胃肠道症状的黄疸性出血是钩端螺旋体病最常见的血清群。另外，最稀有的血清群是canicola和pomona。

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