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Social memory performance in schizophrenia

机译:精神分裂症的社交记忆表现

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The advance of social neurosciences is by and large dependent on the circumscription and measure of specific social-cognitive competencies. The importance of accurate neuropsychological tests emerges in this context as a decisive step to the evolution of the field as a whole. This paper has three interconnected goals: to shed light into a previously unreported social cognitive dimension and to introduce a software-based, multilingual neuropsychological test to assess and quantify performance under it; to validate the test for neurocognitive assessment in schizophrenia and to?establish brain correlates of differences in performance in a cohort of patients with schizophrenia. The competence under consideration is called social memory and this relates to the ability to recall social information. Its conceptual validity stems from differences in performance when recalling human (H) vs. non-human figures (NH). The new test is called social memory test (SMT). Here we present the validation of SMT and its application to assess brain correlates of performance in a cohort of medicated adult patients with schizophrenia using diffusion tensor imaging (DTI). Cronbach’s α was above 0.7 on the clinical sample, and above 0.58 on the control group. Results suggest that the test is a reliable instrument to assess social memory in schizophrenia, and that performance is correlated to visual memory and social cognition. Neuroimaging results warrant an important role to Heschl′s gyrus, thus suggesting that semantic processingis chiefly tied to this social-cognitive competence.
机译:社会神经科学的进步在很大程度上取决于特定社会认知能力的界定和量度。在这种情况下,准确的神经心理学测试的重要性作为整个领域发展的决定性步骤而应运而生。本文具有三个相互关联的目标:阐明以前未曾报道过的社会认知维度,并引入基于软件的多语言神经心理学测试来评估和量化其下的表现;验证精神分裂症患者的神经认知评估测试,并确定一群精神分裂症患者的表现差异与大脑的相关性。所考虑的能力称为社交记忆,这与回忆社交信息的能力有关。它的概念有效性来自召回人类(H)与非人类数字(NH)时性能的差异。新的测试称为社交记忆测试(SMT)。在这里,我们介绍SMT的验证及其在评估使用扩散张量成像(DTI)的成年精神分裂症的成年药物患者队列中的性能与大脑的相关性。临床样本中Cronbach'sα高于0.7,而对照组则高于0.58。结果表明该测试是评估精神分裂症中社交记忆的可靠工具,并且其表现与视觉记忆和社交认知相关。神经影像学结果证明了赫氏回合的重要作用,因此表明语义加工主要与这种社会认知能力有关。

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