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Association between Offset of the Pupil Center from the Corneal Vertex and Wavefront Aberration

机译：小学生中心角膜顶点偏移与波前像差之间的关联

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Purpose: To investigate the influence of offsets of the pupil center from the corneal vertex on wavefront aberrations in the anterior cornea and the whole eye. Methods: Both right and left eyes of 103 subjects were measured for the wavefront aberrations in the anterior cornea, along with the offset of the pupil center relative to the corneal vertex, using a Humphrey corneal topographer, and for the wavefront aberration in the whole eye using a WASCA wavefront sensor. Correlations of the pupil center offsets with the Zernike aberrations were tested. Results: X-axis shift of the pupil center from the corneal vertex was significantly correlated to horizontal coma for both the right (r = 0.54, P<0.0001) and left eyes (r=0.48, P<0.0001) in the cornea, but was weakly correlated to the coma in the whole eye (r=0.17, P=0.04 for OD; and r=0.17, P=0.05 for OS). Significant but weak correlations with the x-axis pupil center shift were also found for several other Zernike aberrations, including the oblique astigmatism, vertical trefoil and secondary astigmatism. Very few Zernike aberrations were significantly correlated to y-axis pupil center shift. Most Zernike aberrations were significantly correlated between the right and left eyes to produce bilateral symmetry in the cornea and the whole eye. Conclusions: The results suggest that offset of the pupil center from the corneal vertex plays an important role in determining horizontal coma and few other Zernike aberrations. Factors controlling bilateral symmetry of the wavefront aberrations between the two eyes could make important contributions to wavefront aberrations in the human eye.
机译：目的：研究瞳孔中心偏离角膜顶点对前角膜和全眼波前像差的影响。方法：使用Humphrey角膜地形图仪，对103名受试者的右眼和左眼测量前角膜波前像差，以及瞳孔中心相对于角膜顶点的偏移，并测量整个眼睛中的波前像差。使用WASCA波前传感器。测试了瞳孔中心偏移量与Zernike像差的相关性。结果：角膜的右眼（r = 0.54，P <0.0001）和左眼（r = 0.48，P <0.0001）的瞳孔中心从角膜顶点的X轴位移与水平昏迷显着相关，但是与整个眼睛的昏迷相关性较弱（OD值r = 0.17，P = 0.04; OS值r = 0.17，P = 0.05）。还发现了其他几种Zernike像差与x轴瞳孔中心偏移的显着但微弱的相关性，包括倾斜散光，垂直三叶形和继发性散光。极少的Zernike像差与y轴瞳孔中心偏移显着相关。大多数Zernike像差在右眼和左眼之间显着相关，从而在角膜和整个眼睛中产生双侧对称。结论：结果表明，瞳孔中心偏离角膜顶点在确定水平昏迷和其他少数Zernike像差中起重要作用。控制两只眼睛之间波前像差的双边对称性的因素可能对人眼中的波前像差做出重要贡献。

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