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首页> 外文期刊>Journal of Optometry >Relationship between vessel diameter and depth measurements within the limbus using ultra-high resolution optical coherence tomography
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Relationship between vessel diameter and depth measurements within the limbus using ultra-high resolution optical coherence tomography

机译：使用超高分辨率光学相干断层扫描在角膜缘内血管直径与深度测量之间的关系

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Purpose To establish a relationship between the diameter and depth position of vessels in the superior and inferior corneo-scleral limbus using ultra-high resolution optical coherence tomography (UHR-OCT). Methods Volumetric OCT images of the superior and inferior limbus were acquired from 14 healthy subjects with a research-grade UHR-OCT system. Differences in vessel diameter and depth between superior and inferior limbus were analyzed using repeated measured ANOVA in SPSS and R. Results The mean (± SD) superior and inferior diameters were 29?±?18?μm and 24?±?18?μm respectively, and the mean (± SD) superior and inferior depths were 177?±?109?μm and 207?±?132?μm respectively. The superior limbal vessels were larger than the inferior ones (RM-ANOVA, p =?0.004), and the inferior limbal vessels were deeper than the superior vessels (RM-ANOVA, p =?0.041). There was a positive linear association between limbal vessel depth and size within the superior and inferior limbus with Pearson correlation coefficients of 0.803 and 0.754, respectively. Conclusion This study demonstrated that the UHR-OCT was capable of imaging morphometric characteristics such as the size and depth of vessels in the limbus. The results of this study suggest a difference in the size and depth of vessels across different positions of the limbus, which may be indicative of adaptations to chronic hypoxia caused by the covering of the superior limbus by the upper eyelid. UHR-OCT may be a useful tool to evaluate the effect of contact lenses on the microvascular properties within the limbus.
机译：目的使用超高分辨率光学相干断层扫描（UHR-OCT）建立上，下角膜巩膜角膜缘血管直径与深度位置之间的关系。方法采用研究级UHR-OCT系统，从14名健康受试者中获取上，下肢的OCT图像。使用重复测量的SPSS和R中的方差分析分析上，下缘之间的血管直径和深度的差异。结果上，下直径的平均（±SD）分别为29？±？18？μm和24？±？18？μm ，平均（±SD）上，下深度分别为177？±？109？μm和207？±？132？μm。上缘血管大于下缘血管（RM-ANOVA，p = 0.004），而下缘血管比上缘血管更深（RM-ANOVA，p = 0.041）。上，下缘的角膜缘血管深度与大小之间存在线性正相关，Pearson相关系数分别为0.803和0.754。结论这项研究表明，UHR-OCT能够成像形态特征，例如角膜缘血管的大小和深度。这项研究的结果表明，在角膜缘不同位置的血管大小和深度存在差异，这可能表明适应了由上眼睑覆盖上角膜缘引起的慢性缺氧。 UHR-OCT可能是评估隐形眼镜对角膜缘微血管特性影响的有用工具。

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