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首页> 外文期刊>Journal of Ophthalmology >Patients with Fuchs Endothelial Dystrophy and Cataract Undergoing Descemet Stripping Automated Endothelial Keratoplasty and Phacoemulsification with Intraocular Lens Implant: Staged versus Combined Procedure Outcomes
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Patients with Fuchs Endothelial Dystrophy and Cataract Undergoing Descemet Stripping Automated Endothelial Keratoplasty and Phacoemulsification with Intraocular Lens Implant: Staged versus Combined Procedure Outcomes

机译：患有Fuchs内皮营养不良和白内障的患者行Desmet剥离自动角膜移植和人工晶状体超声乳化联合人工晶状体植入术：分阶段与联合手术结果

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Purpose. To compare the surgical outcomes of staged and combined phacoemulsification with intraocular lens implant (phaco+IOL) and Descemet stripping automated endothelial keratoplasty (DSAEK) in patients with Fuchs’ endothelial dystrophy and cataract.Setting. Corneoplastic Unit and Eye Bank, Queen Victoria Hospital, East Grinstead, UK.Methods. Retrospective study of patients who had combined phaco+IOL and DSAEK (group 1) or phaco+IOL followed within 2 months by DSAEK (group 2). Patients who had previous eye surgery or any other ocular comorbidities were excluded.Results. There were 28 eyes in group 1 and 31 in group 2. There were no significant differences in the demographics and corneal tissue characteristics of the two groups. The endothelial disc dislocation and rebubbling rate within 1 week in group 1 was 21.42% and in group 2 was 3.2%P=0.04, while the endothelial cell density at 12 months was1510±433for group 1 and1535±482for group 2P=0.89. The mean 12-month logMAR visual acuity was0.28±0.24for group 1 and0.33±0.15for group 2P=0.38.Conclusions. Although the combined procedure seems to be associated with a higher complication rate the final outcomes seem to be similar to both methods.
机译：目的。为了比较Fuchs内皮营养不良和白内障患者分期和联合超声乳化联合人工晶状体植入术（phaco + IOL）和Descemet剥离自动内皮角膜移植术（DSAEK）的手术效果。英国东格林斯特德市维多利亚女王医院角质形成单元和眼库。回顾性研究了在2个月内接受DSAEK（第2组）合并phaco + IOL和DSAEK（第1组）或phaco + IOL的患者。排除曾做过眼科手术或其他眼部合并症的患者。第1组有28只眼，第2组有31只眼。两组的人口统计学和角膜组织特征无明显差异。第一组在1周内内皮圆盘脱位和重新起泡的比率为21.42％，第二组为3.2％P = 0.04，而第1组在12个月时的内皮细胞密度为1510±433，而第2组的内皮细胞密度为1535±482。第一组的平均12个月logMAR视力为0.28±0.24，第二组的平均0.33±0.15，P = 0.38。尽管联合手术似乎与较高的并发症发生率相关，但最终结果似乎与两种方法相似。

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