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首页> 外文期刊>Journal of Oral Microbiology >Porphyromonas gingivalis may interfere with conception in women
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Porphyromonas gingivalis may interfere with conception in women

机译：牙龈卟啉单胞菌可能会干扰女性的受孕

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In this observational and prospective study, we investigated if microbiological and serological markers of periodontitis associated with conception in 256 non-pregnant women (Mage = 29.2 years; range 19–42 years). Clinical oral and gynecological examinations were performed, major periodontal pathogens in the saliva were detected, and serum and saliva antibodies against major periodontal pathogens were analyzed. The follow-up period for becoming pregnant was 12 months. Porphyromonas gingivalis was significantly (p = 0.032) more frequently detected in the saliva among those who did not become pregnant (8.3%) than among those who became pregnant (2.1%). The median levels of salivary P. gingivalis immunoglobulin A (IgA; p = 0.006) and IgG (p = 0.007) antibodies were higher among those who did not become pregnant compared to those who became pregnant. Hazard ratios (HR) for not becoming pregnant were HR = 3.75 (95% confidence interval [CI] 1.01–13.9; p = 0.048) if the subject was polymerase chain react...
机译：在这项观察性和前瞻性研究中，我们调查了256名非妊娠妇女（年龄= 29.2岁;年龄19-42岁）中牙周炎的微生物学和血清学标志物是否与受孕相关。进行临床口腔和妇科检查，检测唾液中的主要牙周病原体，并分析针对主要牙周病原体的血清和唾液抗体。妊娠的随访期为12个月。未怀孕的人（8.3％）的唾液中牙龈卟啉单胞菌的发生率显着（p = 0.032），而未怀孕的人（2.1％）的检出率更高。未怀孕者的唾液牙龈卟啉单胞菌免疫球蛋白A（IgA; p = 0.006）和IgG（p = 0.007）抗体的中位水平高于怀孕者。如果受试者发生聚合酶链反应，则未怀孕的危险比（HR）为HR = 3.75（95％置信区间[CI] 1.01–13.9; p = 0.048）...

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