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首页> 外文期刊>Journal of Oral Microbiology >Probiotic Lactobacillus reuteri has antifungal effects on oral Candida species in vitro
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Probiotic Lactobacillus reuteri has antifungal effects on oral Candida species in vitro

机译：益生菌罗伊氏乳杆菌对口腔念珠菌具有体外抗真菌作用

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Background: An alternative approach for managing Candida infections in the oral cavity by modulating the oral microbiota with probiotic bacteria has been proposed.Objective: The aim was to investigate the antifungal potential of the probiotic bacterium Lactobacillus reuteri (DSM 17938 and ATCC PTA 5289) against six oral Candida species (C. albicans, C. glabrata, C. krusei, C. tropicalis, C. dubliniensis, and C. parapsilosis). Design: The lactobacilli were tested for their ability to co-aggregate with and inhibit the growth of the yeasts assessed by spectrophotometry and the agar overlay inhibition assay. Additionally, the pH was evaluated with microsensors, and the production of hydrogen peroxide (H2O2) by the lactobacilli was verified.Results: Both L. reuteri strains showed co-aggregation abilities with the yeasts. The lactobacilli almost completely inhibited the growth of C. albicans and C. parapsilosis, but did not affect C. krusei. Statistically significant differences in co-aggregation and gr...
机译：背景：提出了通过益生菌调节口腔微生物群来控制口腔念珠菌感染的另一种方法。目的：研究益生菌罗伊氏乳杆菌（DSM 17938和ATCC PTA 5289）的抗真菌潜力六种口腔念珠菌物种（白色念珠菌，glabrata念珠菌，krusei念珠菌，热带念珠菌，dubliniensis念珠菌和副寄生念珠菌）。设计：通过分光光度法和琼脂覆盖抑制试验评估了乳酸杆菌与酵母共聚集和抑制酵母生长的能力。此外，用微传感器评估pH，并验证乳酸杆菌产生过氧化氢（H2O2）。结果：两种罗伊氏乳杆菌菌株均显示出与酵母的共聚集能力。乳酸菌几乎完全抑制白色念珠菌和副念珠菌的生长，但不影响克鲁氏梭菌。共聚合和聚合的统计显著差异...

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