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首页> 外文期刊>Journal of pharmaceutical care. >A Comparative Study of the Prevalence of Bacterial Strains in Early and Late-Onset Ventilator-Associated Pneumonia in Critically Ill Patients
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A Comparative Study of the Prevalence of Bacterial Strains in Early and Late-Onset Ventilator-Associated Pneumonia in Critically Ill Patients

机译：危重患者早期和晚期呼吸机相关性肺炎细菌菌株患病率的比较研究

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Background: This study aims to determine the prevalence of early (less than 4 days of hospitalization) –and late-onset (more than 4 days after hospitalization) ventilator-associated pneumonia in the intensive care units of Al-Zahra center in Isfahan.Methods: Through a prospective study, 100 patients with ventilator-associated pneumonia who were hospitalized in the intensive care units of Al-Zahra hospital during 2015 were investigated, and early and late onset pneumonia were determined. Moreover, the etiology of bacterial strains and other clinical and demographic characteristics were compared in two groups.Results: The patients, 23 and 77 suffered from late –and early-onset pneumonia, respectively. The mean score of pneumonia in the two groups (early –and late-onset pneumonia) was 7.3± 2.1 and 7.2±1.6, respectively, which showed no significant difference (P: 0.8). The most common types of bacteria that caused pneumonia were methicillin-resistant Staphylococcus aureus (MRSA) (43% of frequency) and Acinetobacter Baumannii (34% of frequency) in early –and late-onset pneumonia, respectively. However, the frequency distribution of the type of bacteria by the type of pneumonia was not significantly different (P:0.1).Conclusion: A significant percentage of pneumonia in intensive care units are of early-onset type, which can lead to patients’ prolonged hospitalization in intensive care units and it may be lead to increased mortality rate among them. Therefore, it is recommended that the patients hospitalized in intensive care units should be carefully examined in terms of the occurrence of pneumonia symptoms.
机译：背景：本研究旨在确定伊斯法罕市Al-Zahra中心的重症监护室中呼吸机相关性肺炎的早期（住院少于4天）和晚期发作（住院超过4天）的患病率。 ：通过一项前瞻性研究，调查了2015年在Al-Zahra医院重症监护病房住院的100例呼吸机相关性肺炎患者，并确定了早发和晚发性肺炎。此外，还比较了两组细菌菌株的病因以及其他临床和人口统计学特征。结果：23例和77例患者分别患有晚期和早发性肺炎。两组的肺炎平均得分（早发性肺炎和迟发性肺炎）分别为7.3±2.1和7.2±1.6，差异无统计学意义（P：0.8）。引起肺炎的最常见细菌分别是在早发性和迟发性肺炎中，耐甲氧西林的金黄色葡萄球菌（MRSA）（频率的43％）和鲍曼不动杆菌（频率的34％）。然而，细菌类型的频率分布与肺炎的类型没有显着差异（P：0.1）。结论：重症监护病房中很大比例的肺炎是早发型的，这可能导致患者病情延长重症监护病房的住院治疗可能会导致其中的死亡率上升。因此，建议对重症监护病房住院的患者进行肺炎症状的仔细检查。

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