...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of pharmaceutical care. >The role of Clinical Pharmacists in the improvement of a pharmacovigilance system: A review of the reported adverse drug reactions during 2004-2010 in Mazandaran Province of Iran.
【24h】

The role of Clinical Pharmacists in the improvement of a pharmacovigilance system: A review of the reported adverse drug reactions during 2004-2010 in Mazandaran Province of Iran.

机译：临床药剂师在改善药物警戒系统中的作用：对伊朗Mazandaran省2004-2010年间报告的药物不良反应的评论。

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Following establishment of Iranian Adverse Drug Reaction (ADR) Monitoring Center in 1997, ADR committees were established in all hospitals of Mazandaran Province of Iran. Clinical pharmacists from Mazandaran University of Medical Sciences have been involved with these committees since 2007. The aim of this study was to compare the results of the pharmacovigilance system before and after active involvement of clinical pharmacists.Methods: This study included Yellow Cards filled out by healthcare providers inMazandaran Province during 2004-2010. Frequency of Adverse Drug Reactions (ADRs), route of administration, reporters, number of reports in each years and damaged organs were focuses. Statistical analysis was performed by SPSS 16 software. P< 0.05 was considered as significant difference.Results: A total of 793 yellow cards were completed during 2004 – 2010. Only 38 ADRs(4.8%) were related to 2004-2007. Most of the reports generated by Nurses (49.3%) followed by Pharmacists and Physicians (P< 0.001). Forty-one reactions (5.2%) were serious, most related to Ceftriaxone, Desfonac and Vancomycin.Conclusion: Clinical pharmacists’ intervention regarding establishing ADR committees in the hospitals improved the output of the pharmacovigilance system, although under- reporting is still a major drawback of spontaneous reporting.
机译：背景：自1997年建立伊朗药品不良反应（ADR）监测中心以来，伊朗Mazandaran省所有医院都建立了ADR委员会。自2007年以来，来自Mazandaran医科大学的临床药师就已经参与了这些委员会。本研究的目的是比较临床药师积极参与之前和之后的药物警戒系统的结果。方法：本研究包括由黄牌填写的黄卡2004年至2010年期间，马赞达兰省的医疗保健提供者。药物不良反应的发生频率，给药途径，报告者，每年的报告次数以及受损的器官是重点。统计分析通过SPSS 16软件进行。 P <0.05为差异有统计学意义。结果：2004年至2010年，共完成793张黄牌。2004年至2007年，只有38张ADR（4.8％）与黄牌相关。护士（49.3％），药剂师和医师（P <0.001）紧随其后。严重的反应为41个（5.2％），大多数与头孢曲松，地昔芬和万古霉素有关。结论：临床药剂师对在医院建立ADR委员会的干预提高了药物警戒系统的输出，尽管报告不足仍然是主要缺陷自发报告。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号