• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Pharmaceutics >The Challenges and Knowledge Gaps in Malaria Therapy: A Stakeholder Approach to Improving Oral Quinine Use in the Treatment of Childhood Malaria in Ghana
【24h】

The Challenges and Knowledge Gaps in Malaria Therapy: A Stakeholder Approach to Improving Oral Quinine Use in the Treatment of Childhood Malaria in Ghana

机译：疟疾治疗中的挑战和知识空白：利益相关者方法，以改善口服加奎宁在加纳儿童期疟疾治疗中的使用

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background. The study was undertaken to elicit the knowledge, views, and perceptions of key stakeholders on malaria, its bioburden, and treatment options, in order to ascertain the knowledge gabs and challenges, especially in the use of oral quinine in childhood malaria. Methods. A cross-sectional survey was conducted using a well-structured Likert Scale and self-administered questionnaire. The principal site of the study was a government-run children’s hospital located in the Ashiedu Keteke Sub-Metro of Accra. The study population included health workers, parents, and guardians or care givers. The participants were 300, purposively selected, and consisted of both men (41%) and women (59%) who were twenty years and above, whether employed (42%), self-employed (37%), or unemployed (21%). Results. Majority of the participants (78%) demonstrated above average knowledge of malaria. However, their awareness of the causes, modes of transmission, signs, and symptoms as well as preventive mechanisms of malaria did not result in low incidence of malaria. About 77% of the respondents agreed they would seek treatment within 24 hours once signs and symptoms are detected. Though close to 50% undertook home treatment of malaria, majority eventually sought treatment at hospital or clinic. Above 92% of respondents knew that quinine is used to treat malaria and agreed its bitter taste greatly affects compliance, especially in children. Consequently, 95% of the respondents would be glad if its bitter taste is masked. Conclusion. The study demonstrated the availability of substantial knowledge of the devastating effects of malaria, especially in children. Therefore, there is the need to ensure the availability and utilization of effective paediatric formulations in the fight against malaria. From this study, fast dissolving oral thin film with a good mouth feel, would be the formulation of choice for quinine.
机译：背景。进行该研究旨在了解主要利益相关者对疟疾，其生物负担和治疗方案的知识，看法和看法，以便确定知识上的不足和挑战，尤其是在儿童疟疾中口服奎宁的使用方面。方法。使用结构良好的李克特量表和自我管理的问卷进行横断面调查。研究的主要地点是位于阿克拉Ashiedu Keteke Sub-Metro的政府经营的儿童医院。研究人群包括卫生工作者，父母，监护人或护理人员。参与者是有针对性地选择的300人，包括二十岁及以上的男性（41％）和女性（59％），无论是受雇（42％），自雇（37％）还是失业（21％） ）。结果。大多数参与者（78％）表现出高于平均水平的疟疾知识。但是，他们对疟疾的病因，传播方式，体征和症状以及预防机制的了解并未导致疟疾发病率低。约77％的受访者同意，一旦发现体征和症状，他们将在24小时内寻求治疗。尽管近50％的人接受了疟疾的家庭治疗，但大多数人最终还是在医院或诊所寻求治疗。超过92％的受访者知道奎宁用于治疗疟疾，并同意其苦味会极大地影响依从性，尤其是在儿童中。因此，如果掩盖苦味，则95％的受访者会很高兴。结论。这项研究证明了对疟疾，特别是对儿童的毁灭性影响的大量知识的可获得性。因此，需要在对抗疟疾中确保​​有效的儿科制剂的可用性和利用。根据这项研究，具有良好口感的快速溶解口腔薄膜将成为奎宁的首选配方。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号