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首页> 外文期刊>Journal of nuclear medicine technology >Effective Dose in Nuclear Medicine Studies and SPECT/CT: Dosimetry Survey Across Quebec Province
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Effective Dose in Nuclear Medicine Studies and SPECT/CT: Dosimetry Survey Across Quebec Province

机译：核医学研究和SPECT / CT中的有效剂量：魁北克省的剂量学调查

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The aims of the current study were to draw a portrait of the delivered dose in selected nuclear medicine studies in Québec province and to assess the degree of change between an earlier survey performed in 2010 and a later survey performed in 2014. Methods: Each surveyed nuclear medicine department had to complete 2 forms: the first, about the administered activity in selected nuclear medicine studies, and the second, about the CT parameters used in SPECT/CT imaging, if available. The administered activities were converted into effective doses using the most recent conversion factors. Diagnostic reference levels were computed for each imaging procedure to obtain a benchmark for comparison. Results: The distributions of administered activity in various nuclear medicine studies, along with the corresponding distribution of the effective doses, were determined. Excluding 131I for thyroid studies, 67Ga-citrate for infectious workups, and combined stress and rest myocardial perfusion studies, the remainder of the 99mTc-based studies delivered average effective doses clustered below 10 mSv. Between the 2010 survey and the 2014 survey, there was a statistically significant decrease in delivered dose from 18.3 to 14.5 mSv. 67Ga-citrate studies for infectious workups also showed a significant decrease in delivered dose from 31.0 to 26.2 mSv. The standardized CT portion of SPECT/CT studies yielded a mean effective dose 14 times lower than the radiopharmaceutical portion of the study. Conclusion: Between 2010 and 2014, there was a significant decrease in the delivered effective dose in myocardial perfusion and 67Ga-citrate studies. The CT portions of the surveyed SPECT/CT studies contributed a relatively small fraction of the total delivered effective dose.
机译：当前研究的目的是在魁北克省选定的核医学研究中绘制输送剂量的画像，并评估在2010年进行的较早调查与2014年进行的较晚调查之间的变化程度。医学部门必须完成2种形式：第一种形式，有关选定的核医学研究中的给药活性，第二种形式，有关SPECT / CT成像中使用的CT参数（如果有）。使用最新的转换因子将施用的活性转换为有效剂量。计算每种成像程序的诊断参考水平，以获得比较的基准。结果：确定了各种核医学研究中给药活性的分布以及有效剂量的相应分布。除了用于甲状腺研究的131I，用于传染性检查的67Ga-柠檬酸盐，以及压力与静息心肌灌注研究的结合之外，其余基于99mTc的研究均提供了平均有效剂量，均低于10 mSv。在2010年调查和2014年调查之间，运送剂量从18.3 mSv下降到14.5 mSv，具有统计上的显着下降。 67Ga-柠檬酸盐对感染性检查的研究还显示，递送剂量从31.0毫安下降到26.2毫希沃特。 SPECT / CT研究的标准化CT部分产生的平均有效剂量比该研究的放射性药物部分低14倍。结论：2010年至2014年之间，心肌灌注和67Ga柠檬酸盐研究的有效剂量显着降低。 SPECT / CT研究的CT部分在总有效剂量中所占的比例很小。

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