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首页> 外文期刊>Journal of Proteins and Proteomics >AN INSIGHT INTO THE MOLECULAR STRUCTURE AND FUNCTION OF POLYGALACTURONASE INHIBITING PROTEIN (PGIP)
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AN INSIGHT INTO THE MOLECULAR STRUCTURE AND FUNCTION OF POLYGALACTURONASE INHIBITING PROTEIN (PGIP)

机译:聚半乳糖醛酸酶抑制蛋白(PGIP)的分子结构和功能研究

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Plants lack the system of circulating antibodies, thus defense mechanism in plants depends on the capability of recognition and interaction with the invading pathogenic microorganisms and neutralising their effect via specific interactions. The first barrier of defense in plants is the cell wall made up of pectin consisting of homogalacturonan, rhamnogalacturonan I and rhamnogalacturonan II. The major component of pectin is homogalacturonan. Pathogenic fungi secrete polygalacturonase (PG) to degrade the homopolygalacturonan of cell wall. Thus plants have pathogenesis-related protein in the cell wall to neutralise the effect of PG known as polygalacturonase inhibiting protein (PGIP). The interaction between PGIP and PG is very specific and effective and differs in different pathogenic fungi and plant species due to the components of plant system. The article presents a critical review on the molecular association of PGIP with PG in nature. An insight has been provided for the use of PGIP in the extracellular localization of mature proteins, in the inhibition of fungal infection, as an elicitor of immune response in plants with great economic and agricultural importance across the world.
机译:植物缺乏循环抗体系统,因此植物的防御机制取决于识别入侵病原微生物并与之相互作用的能力,以及通过特异性相互作用中和其作用的能力。植物的第一个防御屏障是由果胶组成的细胞壁,果胶由高半乳糖醛酸聚糖,鼠李糖半乳糖醛酸聚糖I和鼠李糖半乳糖醛酸聚糖II组成。果胶的主要成分是高半乳糖醛酸聚糖。病原真菌分泌聚半乳糖醛酸酶(PG)降解细胞壁的同聚半乳糖醛酸。因此,植物在细胞壁中具有与发病相关的蛋白质,以中和称为多半乳糖醛酸酶抑制蛋白(PGIP)的PG的作用。 PGIP和PG之间的相互作用非常特异性和有效,并且由于植物系统的组成不同,在不同的致病真菌和植物物种中也有所不同。这篇文章对PGIP与PG在自然界中的分子结合提出了重要的评论。 PGIP在成熟蛋白的胞外定位中,在抑制真菌感染方面的用途,为在世界范围内具有重大经济和农业重要性的植物引起免疫应答提供了一种见识。

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