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Near-Infrared Spectroscopy Is Promising to Detect Iliac Artery Flow Limitations in Athletes: A Pilot Study

机译:近红外光谱有望检测运动员的I动脉血流限制:一项初步研究

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Endurance cyclists have a substantial risk to develop flow limitations in the iliac arteries during their career. These flow limitations are due to extreme hemodynamic stress which may result in functional arterial kinking and/or intravascular lesions. Early diagnosis may improve outcome and could prevent the necessity for surgical vascular repair. However, current diagnostic techniques have unsatisfactory sensitivity and cannot be applied during exercise. Near-infrared spectroscopy (NIRS) has shown great diagnostic potential in peripheral vascular disease and might bring a solution since it measures tissue oxygenation in real time during and after exercise. This report describes the first experiences of the application of NIRS in the vastus lateralis muscle during and after maximal graded cycling exercise in ten healthy participants and in three patients with flow limitations due to (1) subtle functional kinking, (2) an intravascular lesion, and (3) severe functional kinking. The results are put into perspective based on an empirically fitted model. Delayed recovery, showing clearly different types of patterns of tissue reoxygenation after exercise, was found in the affected athletes compared with the healthy participants. In the patients that had kinking of the arteries, tissue reoxygenation was clearly more delayed if NIRS was measured in provocative position with flexed hip. In this pilot experiment, clearly distinctive reoxygenation patterns are observed during recovery consistent with severity of flow limitation, indicating that NIRS is a promising diagnostic tool to detect and grade arterial flow limitations in athletes. Our findings may guide research and optimization of NIRS for future clinical application.
机译:耐力骑行者在职业生涯中有很大的风险发展develop动脉的血流限制。这些流量限制是由于极高的血流动力学压力,可能导致功能性动脉扭结和/或血管内病变。早期诊断可以改善预后,并可以避免进行手术血管修复的必要性。但是,当前的诊断技术的灵敏度不令人满意,并且不能在运动期间应用。近红外光谱法(NIRS)已显示出对周围血管疾病的巨大诊断潜力,并可能带来解决方案,因为它可以在运动中和运动后实时测量组织的氧合作用。本报告介绍了在十个健康参与者和三名因(1)细微的功能性扭结,(2)血管内病变, (3)严重的功能性扭结。基于经验拟合模型将结果放到透视图中。与健康参与者相比,在受影响的运动员中发现了延迟恢复,显示出运动后组织复氧的模式明显不同。在患有动脉弯曲的患者中,如果NIRS在髋关节屈曲的刺激位置进行测量,则组织再充氧明显更延迟。在这个试验性实验中,在恢复过程中观察到明显独特的复氧模式,与流量限制的严重程度一致,这表明NIRS是一种有前途的诊断工具,可以检测和分级运动员的动脉流量限制。我们的发现可能指导NIRS的研究和优化,以用于将来的临床应用。

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