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Open Trial of Family-Based Treatment of Anorexia Nervosa for Transition Age Youth

机译:转型期青年的家庭式神经性厌食症开放治疗试验

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Objective This pilot study conducted an open trial of a manualized adaptation to Family-Based Treatment for Transition Age Youth (FBT-TAY) for Anorexia Nervosa (AN). The aims were: (1) determine the acceptability of FBT for TAY; and, (2) establish preliminary effect sizes for the impact of FBT-TAY on eating disorder behaviour and weight restoration. Method Twenty-six participants across two paediatric and one adult hospital site were recruited to participate. Participants completed the Eating Disorder Examination Questionnaire (EDE-Q) at the start of treatment, the end-of-treatment, and three-month follow-up. Results FBT-TAY is an acceptable and feasible treatment to all study therapists as evidenced by their fidelity to the model. FBT-TAY is a feasible and acceptable intervention to transition age youth, given only 27.27% chose treatment as usual over FBT-TAY. Participants presented significant improvement at end-of-treatment and three-months post-treatment (p < .001; ES = 0.34) from baseline on the EDE-Q Global Score. Participants also achieved and maintained weight restoration at the end-of-treatment and three-months post-treatment when compared to baseline (p < .0001, ES = 0.54). Conclusions FBT-TAY, the first manualized AN treatment for TAY, demonstrated feasibility and acceptability with therapists and participants as well as improvement for participants in EDE-Q global score and weight. Given the current dearth of effective treatments for TAY with AN, FBT-TAY is a promising adaptation of FBT. A larger clinical trial with a 12-month follow-up is recommended.
机译:目的这项初步研究进行了一项开放性试验,该试验以手动方式适应神经性厌食症(AN)的以家庭为基础的过渡期青年治疗(FBT-TAY)。目的是:(1)确定FBT对TAY的可接受性; (2)确定FBT-TAY对饮食失调行为和体重恢复的影响的初步效应量。方法招募了来自两个儿科和一个成人医院现场的26名参与者。参与者在治疗开始,治疗结束和三个月的随访中完成了饮食失调检查问卷(EDE-Q)。结果FBT-TAY是所有研究治疗师都能接受且可行的治疗方法,其对模型的忠诚度证明了这一点。 FBT-TAY是过渡期青年的可行且可接受的干预措施,因为与FBT-TAY相比,仅照常选择27.27%的治疗方法。参与者在治疗结束时和治疗后三个月的表现均较EDE-Q全球评分的基线水平有显着提高(p <.001; ES = 0.34)。与基线相比,参与者在治疗结束时和治疗后三个月也达到并维持了体重恢复(p <.0001,ES = 0.54)。结论FBT-TAY是首个针对TAY的手动AN治疗,证明了对治疗师和参与者的可行性和可接受性,以及对EDE-Q总体评分和体重的参与者的改善。鉴于目前缺乏有效的AN治疗TAY的方法,FBT-TAY是一种有前途的FBT适应症。建议进行一项为期12个月的随访的大型临床试验。

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