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首页> 外文期刊>Journal of the Canadian Academy of Child and Adolescent Psychiatry >Prevention of Substance Use in Children/Adolescents with Mental Disorders: A Systematic Review
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Prevention of Substance Use in Children/Adolescents with Mental Disorders: A Systematic Review

机译：预防精神疾病儿童/青少年的物质使用：系统评价

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Objective: We conducted a systematic review to answer the question: Among youth ≤18 years of age with a mental disorder, does substance use prevention compared to no prevention result in reduced rates of substance use/abuse/disorder (SUD)? The review was requested by the Ontario Ministry of Health and Long-term Care through the Canadian Institutes for Health Research Evidence on Tap program. Methods: A four-step search process was used: Search 1 and 2: Randomized controlled trials (RCTs) that evaluated a SUD prevention intervention in individuals with a mental disorder who were: 1) ≤18 years; or, 2) any age. Search 3: Observational studies of an intervention to prevent SUD in those with mental disorder. Search 4: RCTs that evaluated a SUD primary prevention skills-based intervention in high-risk youth ≤18 years. Results: Searches 1 and 2: one RCT conducted in youth was found; Search 3: two observational studies were found. All three studies reported statistically significant reductions in substance use. Search 4: five RCTs were found with mixed results. Methodological weaknesses including inadequate study power may explain the results. Conclusions: Little is known about effective interventions to prevent SUD in youth with a mental disorder. Effective SUD primary prevention programs exist and should be evaluated in this high-risk group.
机译：目的：我们进行了系统的回顾，以回答以下问题：在≤18岁的精神障碍年轻人中，与没有预防措施相比，预防滥用药物是否会导致降低药物滥用/滥用/精神障碍（SUD）的速度？安大略省卫生和长期护理部通过加拿大卫生研究院关于轻敲的研究证据计划要求进行审查。方法：采用四个步骤的搜索过程：搜索1和2：随机对照试验（RCT），该试验评估了对1岁以下18岁以下精神障碍患者的SUD预防干预。或2）任何年龄。搜索3：预防精神障碍患者SUD干预措施的观察性研究。搜索4：RCT评估了18岁以下高风险青年中基于SUD一级预防技能的干预措施。结果：搜索1和2：发现一项在青年中进行的RCT。搜索3：发现了两项观察性研究。所有这三项研究均报告了在物质使用方面的统计显着减少。搜索4：发现5个RCT，结果不一。方法学上的不足，包括研究能力不足，可能会解释结果。结论：对于预防精神障碍青少年SUD的有效干预措施知之甚少。存在有效的SUD一级预防计划，应在此高风险人群中进行评估。

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