首页> 外文期刊>Journal of the Japanese Physical Therapy Association >Effect of Mirror Therapy on Human Primary Motor Cortex Function in Motor Learning
【24h】

Effect of Mirror Therapy on Human Primary Motor Cortex Function in Motor Learning

机译:镜像疗法对运动学习中人原发性运动皮层功能的影响

获取原文
           

摘要

Purpose : The purpose of this study was to test whether the plasticity changes of the primary motor cortex (M1), which has been proposed as a neural basis of motor learning, was induced by mirror therapy. Methods : We investigated by using transcranial magnetic stimulation (TMS) in 12 neurologically healthy subjects. Each subject was asked to rotate two cork-balls in a counter-clockwise direction with non-dominant hand as fast and accuracy as possible and the number of ball-rotation was counted for 30 seconds. After measuring the motor behavior and TMS (Pre), subjects practiced Motor-training intervention of the right hand with mirror visual feedback (MVF) superimposed on the left hand using a mirror box (Post1). Furthermore, the beneficial effects of MVF were disrupted by the continuous theta burst stimulation (cTBS), which is a procedure to suppress local cortical function, over M1 and the occipital cortex (OC) (Post2). Subjects were randomly assigned with the M1 (n=8) and OC group (n=8) by the site where cTBS was applied. Finally, both groups performed another set of mirror therapy intervention (Post3). Results : Mirror therapy significantly improved the motor behavior and increased the excitability in M1. In addition, the motor behavior and cortical excitability were transiently suppressed by cTBS in M1 group but not in OC group. However, subsequent mirror therapy following cTBS could improve the motor behavior and cortical excitability, again. Conclusion : These results have suggested that the cause-effect link between the M1 activity and behavioral improvement in MVF-induced motor learning.
机译:目的:本研究的目的是测试是否通过镜面疗法诱发了作为运动学习的神经基础的初级运动皮层(M1)的可塑性变化。方法:我们使用经颅磁刺激(TMS)对12名神经系统健康的受试者进行了调查。要求每个受试者尽可能快且准确地以不占优势的手沿逆时针方向旋转两个软木球,并计数球旋转数为30秒。在测量了运动行为和TMS(Pre)之后,受试者使用镜盒(Post1)练习了右手的运动训练干预,并在左手上叠加了镜像视觉反馈(MVF)。此外,MVF的有益作用被连续theta爆裂刺激(cTBS)所破坏,cTBS是一种抑制M1和枕叶皮质(OC)(Post2)上的局部皮质功能的程序。通过应用cTBS的位置,将受试者随机分为M1组(n = 8)和OC组(n = 8)。最后,两组都进行了另一组镜面疗法干预(Post3)。结果:镜面疗法可显着改善M1的运动行为并增加其兴奋性。此外,M1组的cTBS短暂抑制了运动行为和皮质兴奋性,而OC组则没有。但是,继cTBS之后进行后续的镜面治疗可以再次改善运动行为和皮层兴奋性。结论:这些结果表明MVF诱导的运动学习中M1活性与行为改善之间的因果关系。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号