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首页> 外文期刊>Journal of Young Pharmacists >Adverse drug reaction and concepts of drug safety in Ayurveda: An overview
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Adverse drug reaction and concepts of drug safety in Ayurveda: An overview

机译：阿育吠陀的药物不良反应和药物安全性概念：概述

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摘要

Drug safety is a very basic and fundamental concept in medical practice. ADRs play an important role in assessing patient safety in any system of medicine. Pharmacovigilance study is thus significant to understand treatment outcomes. Current raised issue with respect to complementary and alternative system medicine (CAM) like Ayurveda is increased in number of safety reports along with report misinterpretation; this generates the negative impact on system. Although, Ayurveda which is holistic system of medicine from India has elaborated the causes and methods of drug-induced consequences along with preventive measures the available data in classical texts is scattered. The compilation and analysis along with modern concept drug safety is need of the hour. Present literature review was conducted from various compendium of Ayurveda and electronic data base with search terms of ‘Vyapad’, ‘Viruddha’, ‘Ahita’, ‘herbeherb interaction’, ‘idiosyncrasy’, ‘Prakritiviruddha’ etc. The reported information was analysed for the possible correlation on concept of ADR and Pharmacovigilance of current science. Overall review demonstrated that drug interaction, iatrogenic, over dose, administration of unsuitable drugs, reprehensive drug administration with respect to disease, complication from five procedural therapies (Panchakarma) and reprehensible preparation of mineral drug are nearer to the modern causes of ADR. Thus, concept of drug safety and ADR is not new to the Ayurveda. The concept “Drug which is not appropriate to be used as medicine”(Abheshaja) of Ayurveda sounds similar as that of modern pharmacovigilance.
机译：药物安全性是医学实践中非常基本的概念。在任何医学系统中，ADR在评估患者安全性方面都起着重要作用。因此，药物警戒性研究对于了解治疗结果具有重要意义。与阿育吠陀等补充和替代系统医学（CAM）有关的当前提出的问题随着报告的误解而增加了安全报告的数量;这会对系统产生负面影响。尽管来自印度的整体医学系统阿育吠陀已经详细阐述了药物引起的后果的原因和方法以及预防措施，但经典文献中的可用数据却很分散。汇编和分析以及现代概念的药物安全性都是小时之需。目前的文献综述来自阿育吠陀（Ayurveda）的各个纲要和电子数据库，其搜索词为“ Vyapad”，“ Viruddha”，“ Ahita”，“草药相互作用”，“异质性”，“ Prakritiviruddha”等。 ADR概念与当前科学的药物警戒性可能存在关联。总体审查表明，药物相互作用，医源性，超剂量，不适当药物的给药，针对疾病的综合药物给药，五种程序疗法（Panchakarma）的并发症以及矿物药物的应受谴责的制剂更接近于ADR的现代病因。因此，药物安全性和ADR的概念对印度草医学并不陌生。阿育吠陀的“不适合用作药物的药物”（Abheshaja）概念听起来与现代药物警戒相似。

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