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Evaluation of Jitter by Stimulated Single-Fiber Electromyography in Normal Dogs

机译:通过刺激的单纤维肌电图评估正常犬的抖动

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Single-fiber electromyography (SFEMG), a technique used to investigate neuromuscular transmission, has been described previously in the pelvic limb of dogs. Because preferential involvement of isolated muscle groups can occur in disorders of neuromuscular transmission, SFEMG waabone in the peroneus longus (PL), extensor carpi radialis (ECR), and orbicularis oculi (OO) muscles of 10 adult, clinically normal dogs. Jitter was calculated as the mean absolute value of the consecutive differences in latency of 50 single muscle fiber action potentials after stimulation of intramuscular nerve bundles at the level of the motor point in at least 20 muscle fibers per muscle. Bilateral recordings were performed in 3 dogs. Mean jitter values were determined for each muscle, and differences among muscle groups and among dogs were compared. The upper limits of mean consecutive difference (mean plus 3 standard deviations) for the PL, ECR, and OO muscles were 21.94, 22.53, and 23.39 μs, respectively, and the upper limit of mean consecutive difference for individual muscle fibers in the respective fiber pools was 28.62, 36.39, and 35.68 (JLs. Jitter values for the ECR and OO were significantly higher than the jitter value for the PL muscle ( P < .05). Significant differences among muscles or dogs or between sides were not observed for the ECR. Significant differences among dogs were observed for OO jitter values and were attributed to extremely low jitter values in 1 dog. Significant differences were demonstrated between sides for the PL and were attributed to small sample size. Results of this study provide normative data that can be used in the application of the stimulated SFEMG technique to dogs with suspected disorders of neuromuscular transmission.
机译:单纤维肌电图(SFEMG),一种用于研究神经肌肉传递的技术,先前已经在狗的骨盆四肢中进行了描述。由于孤立的肌肉群的优先参与可能发生在神经肌肉传递障碍中,因此,十只临床上正常的成年犬的腓骨长臂(PL),radial伸腕(ECR)和眼轮(OO)肌肉中的SFEMG waabone。抖动计算为在肌肉中每运动至少20条肌肉纤维中的运动点水平刺激肌内神经束后,50条单条肌肉纤维动作电位潜伏期连续差异的平均绝对值。在3只狗中进行了双边记录。确定每条肌肉的平均抖动值,并比较肌肉组之间和狗之间的差异。 PL,ECR和OO肌肉的平均连续差异上限(均值加上3个标准差)分别为21.94、22.53和23.39μs,各个纤维中各个肌肉纤维的平均连续差异上限池分别为28.62、36.39和35.68(JLs。ECR和OO的抖动值显着高于PL肌肉的抖动值(P <.05)。 ECR:观察到狗之间的OO抖动值存在显着差异,这归因于1只狗的抖动值极低; PL的两侧之间存在显着差异,这归因于样本量小。可用于受刺激的SFEMG技术在疑似神经肌肉传输障碍的狗中的应用。

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