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首页> 外文期刊>Muscle and Nerve >Repetitive nerve stimulation and single-fiber electromyography in the evaluation of patients with suspected myasthenia gravis or Lambert-Eaton myasthenic syndrome: Review of recent literature
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Repetitive nerve stimulation and single-fiber electromyography in the evaluation of patients with suspected myasthenia gravis or Lambert-Eaton myasthenic syndrome: Review of recent literature

机译：重复性神经刺激和单纤维肌电图评估疑似重症肌无力或兰伯特-伊顿肌无力综合征的患者：最近文献回顾

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Introduction: Our aim in this study was to provide an updated literature review of electrodiagnostic testing in myasthenia gravis and Lambert-Eaton myasthenic syndrome. Methods: A systematic review of the recent literature was performed using the following key words: myasthenia gravis (MG); Lambert-Eaton myasthenic syndrome (LEMS); electromyography (EMG); repetitive nerve stimulation (RNS); single-fiber electromyography (SFEMG); nerve conduction study; and normative values. Results: Several articles supported testing of facial, bulbar, and respiratory muscles in the diagnosis of neuromuscular junction (NMJ) disorders, including muscle-specific kinase antibody (MuSK)-seropositive MG. Several articles supported use of concentric needle EMG as an alternative to SFEMG jitter in disorders of neuromuscular transmission. A limited number of articles addressed measurement of area (vs. amplitude) decrement in RNS and decreasing the threshold of post-exercise facilitation. Conclusions: Electrodiagnostic testing continues to be useful for diagnosis of MG and LEMS, although the quality of the evidence is not great. This literature review summarizes RNS and jitter measurement of facial and respiratory muscles and use of concentric needle EMG for SFEMG. Muscle Nerve 52:455-462, 2015
机译：简介：我们在这项研究中的目的是提供重症肌无力和兰伯特-伊顿肌无力综合征电诊断测试的最新文献综述。方法：使用以下关键词对近期文献进行系统回顾：重症肌无力（MG）; Lambert-Eaton重症肌无力综合征（LEMS）;肌电图（EMG）;重复性神经刺激（RNS）;单纤维肌电图（SFEMG）;神经传导研究;和规范价值。结果：数篇文章支持对面部，延髓和呼吸肌的测试，以诊断神经肌肉接头（NMJ）疾病，包括肌肉特异性激酶抗体（MuSK）-血清阳性MG。几篇文章支持在神经肌肉传播疾病中使用同心针肌电图替代SFEMG抖动。数量有限的文章讨论了RNS中面积（相对于幅度）递减的测量以及降低运动后促进的阈值。结论：尽管证据质量不佳，电诊断测试仍可用于诊断MG和LEMS。该文献综述总结了面部和呼吸肌的RNS和抖动测量以及同心针肌电图用于SFEMG。肌肉神经52：455-462，2015

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