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首页> 外文期刊>Journal of Young Pharmacists >Development of Broad-Spectrum Natural Sunscreens using Combinations of five Plant Species
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Development of Broad-Spectrum Natural Sunscreens using Combinations of five Plant Species

机译：结合五种植物开发广谱天然防晒霜

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Introduction: Cancer is a range of multifactorial diseases which have in common uncontrolled increase in the number of cells invading various tissues and organs. One of its leading etiological agents is sun exposure, and therefore the use of sunscreens plays an important role in cancer prevention. Objective : In this context, the aim of this study was to verify whether the selected naturally-derived raw materials (Oli-ola dry extract, Hibiscus dry extract, Raspberry ketones, Leucoanthocyanidins isolated from grapes and Resveratrol) present adequate photoprotective properties for the development of an innovative broad-spectrum sunscreen. Methods: The determination of sunscreen activity was made in vitro , and the following parameters were obtained: Sun Protection Factor (SPF), UVA Protection Factor (UVAPF), Critical Wavelength and Boots Star Rating. Results: Innovative products showed varied results (maximum SPF=46; maximum UVAPF=22), being that all of them showed to be promising for both parameters. However, the greatest protection was shown in the UVB region. Conclusion: Thus, the Oli-Ola, Hibiscus, Leucoanthocyanidins, Raspberry Ketones and Resveratrol species, grouped in a cosmetic base lotion, showed potential for the development of innovative sunscreen products. Additionally, the SPF should be confirmed in vivo .
机译：简介：癌症是一系列多因素疾病，它们侵袭各种组织和器官的细胞数量通常不受控制地增加。它的主要病因之一是日晒，因此使用防晒霜在预防癌症中起着重要作用。目的：在此背景下，本研究的目的是验证所选的天然来源原料（奥利-奥拉干提取物，芙蓉干提取物，覆盆子酮，从葡萄中分离出的白花色素和白藜芦醇）是否具有足够的光防护性能来促进发育创新的广谱防晒霜。方法：在体外测定防晒活性，并获得以下参数：防晒系数（SPF），紫外线防护系数（UVAPF），临界波长和靴星等级。结果：创新产品显示出不同的结果（最大SPF = 46;最大UVAPF = 22），因为所有产品均显示出对这两个参数都有希望。但是，在UVB区域显示出最大的保护作用。结论：因此，归入化妆品基础乳液中的Oli-Ola，Hibiscus，Leucoanthocyanidins，Raspberry Ketones和Resveratrol物种显示出开发创新防晒产品的潜力。另外，应该在体内确认SPF。

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