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首页> 外文期刊>Journal of Young Pharmacists >Essential Medication Prescription and Associated Maternal Characteristic among Hospitalized Pregnant Women: A Retrospective Population Based Study
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Essential Medication Prescription and Associated Maternal Characteristic among Hospitalized Pregnant Women: A Retrospective Population Based Study

机译：住院孕妇的基本药物处方和相关的孕妇特征：一项基于回顾性人群的研究

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Objective: There are limitations of Food and Drug Administration pregnancy risk classification system and pregnancy information, surplus resources are essential to evaluate the safety and to assess the risk-benefit ratio of medication use in pregnancy. The aim of the study is to characterize medication use in hospitalized pregnant women during antenatal period and correlate maternal characteristics in this population. Methods: It is a retrospective cross-sectional survey. Data of hospitalized pregnant women was collected. The FDA pregnancy risk classification was categorized for the prescribed drugs. Descriptive analysis was performed for demographic and maternal characteristics. Pearson Chi-square Fisher’s exact tests are used to observe the association between the independent variables and outcome variables. Adjusted odds ratios (ORs) and 95% CIs were also estimated. Each outcome variables whose levels were with a P (< 0.05) was significant. Results: Among 505 pregnant women, 75.24% were hospitalized during third trimester, and 3.17% were having comorbid conditions. 60.59% of the pregnant women received more than or equal to five drugs. 39.86% are exposed to FDA C, D or X categories of drugs during pregnancy. Category B drugs are frequently prescribed. Women whose parity is ≥ 2, length of hospital stay and with at least five medications prescribed are the factors associated to prescription of FDA C, D or X drugs during pregnancy. Conclusion: There was considerable use of medicines among the pregnant women as per the essential drug list complying fully with World Health Organization recommendations by using their international non-proprietary names.
机译：目的：美国食品和药物管理局怀孕风险分类系统和怀孕信息存在局限性，多余的资源对于评估安全性和评估怀孕用药的风险收益率至关重要。这项研究的目的是确定住院孕妇在产前的用药特点，并与这一人群的孕产妇特征相关。方法：这是一项回顾性横断面调查。收集住院孕妇的数据。 FDA对处方药进行了妊娠风险分类。对人口和孕产妇特征进行描述性分析。皮尔森·卡方·费舍尔（Pearson Chi-square Fisher）的精确检验用于观察自变量与结果变量之间的关联。还估计了调整后的优势比（OR）和95％CI。每个结果变量的水平均以P（<0.05）为显着水平。结果：在505名孕妇中，妊娠中期住院的比例为75.24％，合并疾病的比例为3.17％。 60.59％的孕妇接受了五种或以上的药物。 39.86％在怀孕期间接触FDA C，D或X类药物。经常开B类药物。胎龄≥2，住院时间长且至少开了五种药物的妇女与怀孕期间使用FDA C，D或X药物的处方有关。结论：根据基本药物清单，孕妇中使用了大量药物，完全符合世界卫生组织的建议，使用的是国际非专有名称。

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