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首页> 外文期刊>Journal of Young Pharmacists >Monitoring the Prevalence of Metabolic Syndrome Among Hypothyroid Patients and Assessing the Effect of Anti-Hypothyroid Treatment on it Among the South Indian Population
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Monitoring the Prevalence of Metabolic Syndrome Among Hypothyroid Patients and Assessing the Effect of Anti-Hypothyroid Treatment on it Among the South Indian Population

机译：监测甲状腺功能减退患者中代谢综合征的患病率，并评估抗甲状腺功能减退对其南部印度人群的治疗效果

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Objective: Hypothyroidism and metabolic syndrome are well associated risk factors for atherogenic cardiovascular diseases. This study was intended to investigate the prevalence of metabolic syndrome and to assess its related parameters in hypothyroid patients. Material and Methods: Study was conducted in ENT department of a tertiary care teaching hospital. Thirty patients diagnosed with hypothyroidism of age 12-40 years of both sexes were screened for metabolic and thyroid parameters. Among them, who were diagnosed with metabolic syndrome according to IDF criteria were included in the study. The baseline patients were treated with L-thyroxin and reviewed after 3 months. Baseline and reviewed parameters were compared. Data were analyzed with paired ‘t’ test. Results: The mean age of the study population was found to be 26.9 ± 8.1 years and among the study population 96.66% were female. Among the study population (n=30), 13 patients were diagnosed with metS according to the IDF criteria and data from these patients was used as the baseline, after L-Thyroxine treatment for three months it was found that around 70% were out of metS. Statistical result shows the significant changes in metabolic parameters with treatment. Further the association of metabolic and thyroid parameters were also found. Conclusion: Present study shows that the female have higher prevalence of hypothyroidism. Further study results show significant association between hypothyroidism and metabolic syndrome which necessitates the need for monitoring thyroid functions in patients with metabolic syndrome.
机译：目的：甲状腺功能减退症和代谢综合征是动脉粥样硬化性心血管疾病的相关危险因素。这项研究旨在调查代谢综合征的患病率，并评估其在甲状腺功能减退患者中的相关参数。材料与方法：研究是在三级教学医院耳鼻喉科进行的。筛查了30名年龄在12-40岁之间的甲状腺功能减退症患者的代谢和甲状腺参数。其中，根据IDF标准被诊断出患有代谢综合征的人包括在研究中。基线患者接受L-甲状腺素治疗，并在3个月后复查。比较基线和审查的参数。使用配对的“ t”检验分析数据。结果：发现研究人群的平均年龄为26.9±8.1岁，在研究人群中女性为96.66％。在研究人群（n = 30）中，根据IDF标准将13例患者诊断为metS，并将这些患者的数据作为基线，在L-甲状腺素治疗3个月后，发现约有70％ metS。统计结果表明，随着治疗代谢参数的显着变化。此外，还发现了代谢和甲状腺参数的关联。结论：目前的研究表明，女性甲状腺功能减退症的患病率较高。进一步的研究结果表明，甲状腺功能减退症与代谢综合征之间存在显着关联，因此有必要监测代谢综合征患者的甲状腺功能。

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