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Assessment of Prescribing Pattern for Hypertension and Comparison with JNC-8 Guidelines-Proposed Intervention by Clinical Pharmacist

机译:评估高血压的处方模式,并与JNC-8指南提议的临床药剂师干预措施进行比较

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Background: Hypertension is a common disorder that if not effectively treated results in greatly increased probability of coronary thrombosis, strokes, and renal failures. It is estimated that the prevalence of hypertension in India is about 25% among urban adults and 10% in the rural areas. The lifetime risk of developing hypertension is estimated to be 90%. To assess prescribing pattern in hypertensive patients and assessing the rationality in regards to JNC-8 Guidelines in a tertiary care hospital. Methodology: It was a prospective, observational study conducted for 6 months with of 75 hypertensive prescriptions with diabetes mellitus and/ or chronic kidney disease who get admitted in the hospital were screened for the study. Result: In a total of 75 prescriptions, 14 (18.7%) prescriptions were found in the age group of less than 50 years, in which 10 (13.3%) were males and 4 (5.4%) were females and 36 (48%) prescriptions were comes under the age group between 51–65 years, in which 26 (34.7%) were males and 10 (13.3%) were females. Also 25 (33.3%) prescriptions were comes under the age group of above 65 years, in which 20 (26.7%) were males and 5 (6.7%) were females. Among mono therapy 22 (47.8%) prescriptions had diuretics as antihypertensive drug followed by CCB 11 (24%), ARBs 7 (15.1%), β blockers 3 (6.5%), ACEIs 1 (2.2%), α blockers 1 (2.2%) and α+β blockers 1 (2.2%). When compared with JNC 8 Guidelines it was observed that 28% of prescriptions were rational and 56% of prescriptions were irrational. Regarding the perception of physicians towards JNC 8 guidelines it was found that majority were not following JNC 8 guidelines.
机译:背景:高血压是一种常见的疾病,如果不进行有效治疗,会大大增加冠状动脉血栓形成,中风和肾功能衰竭的可能性。据估计,印度的高血压患病率在城市成年人中约为25%,在农村地区约为10%。终生患高血压的风险估计为90%。评估高血压患者的处方模式,并评估三级医院关于JNC-8指南的合理性。方法:这是一项前瞻性观察性研究,对在医院入院的75例患有糖尿病和/或慢性肾脏病的高血压处方进行了为期6个月的研究。结果:在总共75张处方中,年龄在50岁以下的人群中发现了14张(18.7%)处方,其中男性10张(13.3%),女性4张(5.4%),36张(48%)。处方属于51-65岁年龄段,其中男性26(34.7%),女性10(13.3%)。 65岁以上的年龄组还有25(33.3%)个处方,其中男性20(26.7%),女性5(6.7%)。在单一疗法中,有22种(47.8%)处方使用利尿剂作为降压药,其次是CCB 11(24%),ARB 7(15.1%),β受体阻滞剂3(6.5%),ACEI 1(2.2%),α阻滞剂1(2.2 %)和α+β受体阻滞剂1(2.2%)。与JNC 8指南相比,观察到28%的处方是合理的,而56%的处方是不合理的。关于医师对JNC 8准则的看法,发现大多数人未遵循JNC 8准则。

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