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首页> 外文期刊>Journal of Thoracic Disease >Associations between mean arterial pressure and 28-day mortality according to the presence of hypertension or previous blood pressure level in critically ill sepsis patients
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Associations between mean arterial pressure and 28-day mortality according to the presence of hypertension or previous blood pressure level in critically ill sepsis patients

机译：重症脓毒症患者中根据高血压的存在或以前的血压水平，平均动脉压与28天死亡率之间的关联

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Background: We aimed to investigate the association between average mean arterial pressure (a-MAP) and mortality in critically ill sepsis patients according to the presence of hypertension and previously measured blood pressure (BP). Methods: From August 2008 to September 2014, patients with severe sepsis or septic shock presenting to the ED were categorized into four groups according to a-MAP during the initial 24 hours (group 0, a-MAP 85 mmHg. The primary outcome was 28-day mortality. Results: A total of 1,395 patients were included. The 28-day mortality rates were 15.1% in patients overall, 39.7% in group 0, 18.3% in group 1, 10.1% in group 2, and 13.4% in group 3. In the regression analyses, mortality in group 2 was significantly lower compared with group 1 [odds ratio (OR), 0.33] or group 3 (OR, 0.31) in patients with hypertension. In the low previous BP group, there was greater mortality in group 3 compared to group 1 (OR, 2.42) and group 2 (OR, 3.88). In the high previous BP group, mortality was lower in group 2 compared with group 1 (OR, 0.32). Conclusions: In critically ill sepsis patients, there were different trends in mortality according to a-MAP depending on the presence of hypertension or previous BP.
机译：背景：我们的目的是根据高血压和先前测得的血压（BP）来研究重症脓毒症患者的平均动脉压（a-MAP）与死亡率之间的关系。方法：从2008年8月至2014年9月，将在ED期间出现严重脓毒症或脓毒性休克的患者在最初的24小时内根据a-MAP分为四组（0组，a-MAP 85 mmHg，主要结局为28结果：总共纳入1,395例患者，其28天死亡率分别为：总患者的15.1％，0组的39.7％，1组的18.3％，2组的10.1％和23.4％ 3.在回归分析中，与高血压组相比，第2组的死亡率明显低于第1组[优势比（OR），0.33]或第3组（OR，0.31），而先前的低血压组则更高。第3组的死亡率高于第1组（OR，2.42）和第2组（OR，3.88）;在先前较高的BP组中，第2组的死亡率比第1组（OR，0.32）低。败血症患者，根据高血压或既往血压的存在，根据a-MAP的死亡率有不同的趋势。

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