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首页> 外文期刊>Journal of spectroscopy >The Drug Metabolism and Pharmacokinetics Investigation about Baicalin Effect and Baicalein on Mice U14 Cervical Cancer
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The Drug Metabolism and Pharmacokinetics Investigation about Baicalin Effect and Baicalein on Mice U14 Cervical Cancer

机译：黄ical苷和黄ical苷对小鼠U14宫颈癌的药物代谢和药代动力学研究

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摘要

The experiment studies the effect of baicalin and baicalein on mice U14 cervical cancer and its pharmacokinetics in mice. By using different mouse models of cancer treatment program administered and uptake kinetics experiments, tissue distribution experiment, excretion, and metabolism in experimental experiments, we found that baicalin and baicalein can improve immunity and the ability of antioxidation and inhibit the growth of tumor. The absorption of intestinal drug takes place in intestinal tract. Tissue distribution was ideal. Because of the ideal drug distribution, the liver and kidney were protected. Drug was mainly excreted through the feces and bile excretion.
机译：该实验研究了黄ical苷和黄ical苷对小鼠U14宫颈癌的影响及其在小鼠体内的药代动力学。通过使用不同的癌症治疗模型小鼠模型进行给药实验以及吸收动力学实验，组织分布实验，排泄和代谢实验，我们发现黄ical苷和黄ical苷可以提高免疫力和抗氧化能力，并抑制肿瘤的生长。肠道药物的吸收发生在肠道中。组织分布是理想的。由于理想的药物分布，肝脏和肾脏得到了保护。药物主要通过粪便和胆汁排出。

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