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首页> 外文期刊>BMJ Open >Synergistic effect of interaction between perceived health and social activity on depressive symptoms in the middle-aged and elderly: a population-based longitudinal study
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Synergistic effect of interaction between perceived health and social activity on depressive symptoms in the middle-aged and elderly: a population-based longitudinal study

机译：感知健康与社会活动之间的交互作用对中老年人抑郁症状的协同效应：一项基于人群的纵向研究

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Objective To examine the synergistic effect of interaction between perceived health and social activity on depressive symptoms. Methods We investigated whether the interaction between perceived health and social activity has a synergistic effect on depressive symptoms in the middle-aged and elderly using data from 6590 respondents aged 45 and older in the Korean Longitudinal Study on Aging (KLoSA), 2006–2012. A generalised linear mixed-effects model was used to investigate the association in a longitudinal data form. Depressive symptoms were measured using the Center for Epidemiological Studies Depression 10 Scale (CES-D10). Perceived health and level of social activity were categorical variables with three values. Participation in six social activities was assessed. Results Interactions between perceived health status and social activity were statistically significant for almost all social activity/perceived health combinations. Addition of the interaction term significantly decreased CES-D10 scores, confirming the synergistic effect of the interaction between perceived health status and social activity (‘normal×moderate’, β=?0.1826; ‘poor×moderate’, β=?0.5739; ‘poor×active’, β=?0.8935). In addition, we performed stratified analyses by region: urban or rural. In urban respondents, the additional effect of the interaction term decreased CES-D10 scores and all social activity/perceived health combinations were statistically significant (‘normal×moderate’, β=?0.2578; ‘normal×active’, β=?0.3945; ‘poor×moderate’, β=?0.5739; ‘poor×active’, β=?0.8935). In rural respondents, only one social activity/perceived health combination was statistically significant, and the additional effect of the interaction term showed no consistent trend on CES-D10 scores. Conclusions The interaction between perceived health and social activity has a synergistic effect on depressive symptoms; the additional effect of the interaction term significantly decreased CES-D10 scores in our models.
机译：目的探讨健康意识和社交活动之间相互作用对抑郁症状的协同作用。方法我们使用2006-2012年韩国老龄化纵向研究（KLoSA）中来自6590名年龄在45岁以上的受访者的数据，调查了感知到的健康与社交活动之间的相互作用是否对中老年人的抑郁症状具有协同作用。使用广义线性混合效应模型以纵向数据形式研究关联。抑郁症状使用流行病学研究中心的10级抑郁量表（CES-D10）进行测量。感知健康和社会活动水平是具有三个值的分类变量。评估了参加六项社会活动。结果对于几乎所有社交活动/感知健康组合，感知到的健康状况与社交活动之间的相互作用在统计学上均具有统计学意义。交互作用项的增加显着降低了CES-D10得分，证实了感知到的健康状况与社交活动之间的交互作用的协同效应（“正常×中等”，β=？0.1826;“差×中等”，β=？0.5739;'差x有效”，β=？0.8935）。此外，我们按地区进行了分层分析：城市还是农村。在城市受访者中，交互作用项的额外影响降低了CES-D10得分，并且所有社交活动/感知的健康组合均具有统计学意义（“正常×中等”，β=？0.2578;“正常×活跃”，β=？0.3945; “差×中等”，β＝？0.5739;“差×活跃”，β＝？0.8935）。在农村受访者中，只有一种社交活动/感知健康组合具有统计学意义，并且交互作用项的附加影响表明，CES-D10分数没有一致的趋势。结论感知的健康与社会活动之间的相互作用对抑郁症状具有协同作用。在我们的模型中，交互作用项的附加影响显着降低了CES-D10分数。

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