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首页> 外文期刊>British Journal of Cancer >Transplantation of Human Tumour to Immune Deprived Mice Treated with Anti-thymocyte Serum
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Transplantation of Human Tumour to Immune Deprived Mice Treated with Anti-thymocyte Serum

机译:用抗胸腺细胞血清治疗将人肿瘤移植到免疫缺陷小鼠中

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Five out of 18 primary explants of human carcinomata obtained at operation have been grown progressively for a minimum of one month in thymectomized, x-irradiated mice reconstituted with syngeneic bone marrow and subsequently treated also with anti-thymocyte serum. All the tumours which proliferated were of gastrointestinal origin, growing locally but not metastasizing although direct invasion of the ribs occurred in one case. No implanted breast carcinomata grew in this system.
机译:在手术中获得的18种人癌原代外植体中,有5种已经在经同基因骨髓重构的经胸腺切除,x射线照射的小鼠中逐步生长了至少一个月,并随后用抗胸腺细胞血清处理。所有增生的肿瘤都是胃肠道起源的,尽管在一个病例中发生了肋骨的直接侵袭,但在局部生长但未转移。在该系统中没有植入的乳腺癌生长。

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