Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1

J Adélaide; G Monges; C Dérdérian; J-F Seitz; D Birnbaum

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Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1

机译：食道癌与人细胞周期蛋白D基因CCND1 / PRAD1的扩增

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The human CCND1/PRAD1 gene, located in the 11q13 chromosomal region, encodes a cyclin D protein with potential oncogenic capacity and is involved in several human malignancies. The amplification and expression status of CCND1 was investigated in a series of oesophageal tumours. CCND1 is amplified in 54% and overexpressed in 63% of the tumours of the squamous cell type.

机译：位于11q13染色体区域的人类CCND1 / PRAD1基因编码具有潜在致癌能力的细胞周期蛋白D蛋白，并参与多种人类恶性肿瘤。在一系列食道肿瘤中研究了CCND1的扩增和表达状态。 CCND1在鳞状细胞类型的肿瘤中有54％的扩增和63％的过表达。

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《British Journal of Cancer》 |1995年第1期|共5页
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J Adélaide; G Monges; C Dérdérian; J-F Seitz; D Birnbaum;
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中图分类肿瘤学;
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专利

1. Mechanism of cyclin D1 (CCND1, PRAD1) overexpression in human cancer cells: analysis of allele-specific expression. [J] . Hosokawa Y, Arnold A Genes, Chromosomes and Cancer . 1998,第1期

机译：人癌细胞中细胞周期蛋白D1（CCND1，PRAD1）过表达的机制：等位基因特异性表达的分析。
2. Evaluation of CCND1 amplification and CyclinD1 expression: diffuse and strong staining of CyclinD1 could have same predictive roles as CCND1 amplification in ER positive breast cancers [J] . Zhishuang Li, Jingjing Cui, Qiong Yu, American Journal of Translational Research . 2016,第1期

机译：CCND1扩增和CyclinD1表达的评估：ER阳性乳腺癌中CyclinD1的弥漫性和强染色可能具有与CCND1扩增相同的预测作用
3. Cooperative and differential effects of estrogen, prolactin, 22k and 20khuman growth hormones on cyclin D1/PRAD1 gene expression in T-47D humanbreast cancer cells [J] . Kaneko H., Fujikawa T., Alam KSM., Biochemistry and Molecular Biology International . 1998,第2期

机译：雌激素，催乳激素，22k和20k人类生长激素对T-47D人乳腺癌细胞中cyclin D1 / PRAD1基因表达的协同作用和差异作用
4. Towards Real-Time Detection of Squamous Pre-Cancers from Oesophageal Endoscopic Videos [C] . Xiaohong Gao, Barbara Braden, Stephen Taylor, IEEE International Conference on Machine Learning and Applications . 2019

机译：从食管内窥镜视频走向鳞癌的实时检测
5. Restriction landmark genomic scanning to identify novel methylated and amplified DNA sequences in human lung cancer. [D] . Dai, Zunyan. 2002

机译：限制性地标基因组扫描，以鉴定人类肺癌中新的甲基化和扩增的DNA序列。
6. Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1. [O] . J. Adélaide, G. Monges, C. Dérdérian, 1995

机译：食道癌和人细胞周期蛋白D基因CCND1 / PRAD1的扩增。
7. Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1. [O] . Adélaide, J., Monges, G., Dérdérian, C., 1995

机译：食道癌和人细胞周期蛋白D基因CCND1 / PRAD1的扩增。

Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1

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