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首页> 外文期刊>British Journal of Cancer >Sample size: how many patients are necessary?
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Sample size: how many patients are necessary?

机译:样本量:需要多少患者?

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The need for sample size calculations is briefly reviewed: many of the arguments against small trials are already well known, and we only cursorily repeat them in passing. Problems that arise in the estimation of sample size are then discussed, with particular reference to survival studies. However, most of the issues which we discuss are equally applicable to other types of study. Finally, prognostic factor analysis designs are discussed, since this is another area in which experience shows that far too many studies are of an inadequate size and yield misleading results.
机译:简要回顾了对样本量计算的需求:许多反对小型试验的论点已经众所周知,我们只是粗略地重复了一下。然后讨论了估计样本量时出现的问题,特别是针对生存研究。但是,我们讨论的大多数问题同样适用于其他类型的研究。最后,讨论了预后因素分析设计,因为这是另一个领域,经验表明,太多的研究规模不足,并且会产生误导性的结果。

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