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首页> 外文期刊>British Journal of Cancer >Effect of age and sex on lung-colony-forming efficiency of injected mouse tumour cells
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Effect of age and sex on lung-colony-forming efficiency of injected mouse tumour cells

机译:性别对注射的小鼠肿瘤细胞肺集落形成效率的影响

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The i.v. injection of a specified number of cells of either an Ehrlich ascites tumour (ELD) or spontaneous mouse mammary adenocarcinomas (MA) into C3H mice yielded a number of lung colonies which varied significantly with the age or sex of recipient mice. The yield was higher in mice of 71 weeks than in those of 15 weeks, except for MA cells injected into females, when the yield was higher in the younger mice. Sex did not influence very significantly the yield of colonies from ELD cells, in the case of MA cells the direction of sex differences depended on age. A difference in the effect of pre-immunization with age was not observed.
机译:i.v.在C3H小鼠中注射指定数量的Ehrlich腹水肿瘤(ELD)或自发性小鼠乳腺腺癌(MA)的细胞会产生许多肺集落,其随受体小鼠的年龄或性别而变化。 71周龄小鼠的产量高于15周龄小鼠,但注入雌性的MA细胞除外,而年轻小鼠的产量较高。性别对ELD细胞集落的产量影响不大,在MA细胞中,性别差异的方向取决于年龄。未观察到免疫接种的效果随年龄的变化。

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