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首页> 外文期刊>British Journal of Cancer >Vitamin K and childhood cancer: a report from the United Kingdom Childhood Cancer Study
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Vitamin K and childhood cancer: a report from the United Kingdom Childhood Cancer Study

机译：维生素K与儿童期癌症：英国儿童期癌症研究的报告

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The relationship between neonatal vitamin K received by the intramuscular (i.m.) route and the development of leukaemia or other cancers was investigated as part of a national case–control study of childhood cancer, using data abstracted from obstetric and neonatal records. The analyses included 2530 children diagnosed with cancer before 15 years of age, 1174 of whom had leukaemia and 4487 control children without cancer. Overall, 39% of cases and 42% of controls had records of i.m. vitamin K administration, while 24% of cases and 22% of controls had no record of whether or not they had received vitamin K. Using subjects who received i.m. vitamin K as the baseline group, our analyses found no association between the administration of i.m. vitamin K and either leukaemia or other cancers as a group. We conclude that there is no convincing evidence that neonatal vitamin K administration, irrespective of the route by which it is given, influences the risk of children developing leukaemia or any other cancer.
机译：通过从产科和新生儿记录中摘录的数据，作为儿童期癌症国家病例对照研究的一部分，研究了肌内（i.m.）途径接受的新生儿维生素K与白血病或其他癌症发生之间的关系。分析包括2530名15岁之前被诊断患有癌症的儿童，其中1174名患有白血病，以及4487名没有癌症的对照儿童。总体而言，有39％的病例和42％的对照有i.m记录。服用维生素K的人中，有24％的病例和22％的对照组没有他们是否接受过维生素K的记录。维生素K作为基线组，我们的分析发现，在进行i.m.维生素K和白血病或其他癌症。我们得出的结论是，没有令人信服的证据表明，无论给与何种途径，新生儿服用维生素K都会影响儿童患上白血病或任何其他癌症的风险。

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