Time dependence of biomarkers: non-proportional effects of immunohistochemical panels predicting relapse risk in early breast cancer

J Stephen; G Murray; D A Cameron; J Thomas; I H Kunkler; W Jack; G R Kerr; T Piper; C L Brookes; D W Rea; C J H van de Velde; A Hasenburg; C Markopoulos; L Dirix; C Seynaeve; J M S Bartlett

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Time dependence of biomarkers: non-proportional effects of immunohistochemical panels predicting relapse risk in early breast cancer

机译：生物标志物的时间依赖性：免疫组化专家小组预测早期乳腺癌复发风险的非比例效应

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Background:We investigated the impact of follow-up duration to determine whether two immunohistochemical prognostic panels, IHC4 and Mammostrat, provide information on the risk of early or late distant recurrence using the Edinburgh Breast Conservation Series and the Tamoxifen vs Exemestane Adjuvant Multinational (TEAM) trial.

机译：背景：我们调查了随访时间的影响，以确定两个免疫组织化学预后小组（IHC4和Mammostrat）是否可以使用爱丁堡乳房保护系列和他莫昔芬vs依西美坦佐剂跨国公司（TEAM）提供有关早期或晚期远处复发风险的信息。试用。

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《British Journal of Cancer》 |2014年第12期|共6页
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J Stephen; G Murray; D A Cameron; J Thomas; I H Kunkler; W Jack; G R Kerr; T Piper; C L Brookes; D W Rea; C J H van de Velde; A Hasenburg; C Markopoulos; L Dirix; C Seynaeve; J M S Bartlett;
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1. Markers of progression in early-stage invasive breast cancer: a predictive immunohistochemical panel algorithm for distant recurrence risk stratification [J] . Aleskandarany Mohammed A., Soria D., Green A. R., Breast cancer research and treatment. . 2015,第2期

机译：早期浸润性乳腺癌进展的标志：远距离复发风险分层的预测性免疫组织化学专家组算法
2. Predictive Immunohistochemical Biomarkers in the Context of Neoadjuvant Therapy for Breast Cancer [J] . Daniele Generali, William F. Symmans, Alfredo Berruti JNCI Monographs . 2011,第43期

机译：乳腺癌新辅助疗法中的预测性免疫组织化学生物标志物
3. Cyclin B is an immunohistochemical proliferation marker which can predict for breast cancer death in low-risk node negative breast cancer. [J] . Koliadi A, Nilsson C, Holmqvist M, Acta oncologica. . 2010,第6期

机译：细胞周期蛋白B是一种免疫组织化学增殖标志物，可以预测低危淋巴结阴性乳腺癌中的乳腺癌死亡。
4. Serum Biomarker Concentrations in Benign Breast Conditions and Ductal Carcinoma In Situ: Designing a Diagnostic Biomarker Panel That Can Distinguish Between Benign Conditions and Invasive Breast Cancer [C] . David E. Reese, Meredith C. Henderson, Susan Yeh, Molecular Medicine TRI-CON. . 2014

机译：血清生物标志物浓度在良性乳腺条件和导管癌原位：设计诊断生物标志物面板，可以区分良性条件和侵袭性乳腺癌
5. Dietary associations with biomarkers of breast cancer risk in women on adjuvant tamoxifen therapy. [D] . Strom, Meghan Brianna. 2016

机译：辅助性他莫昔芬治疗妇女饮食中与乳腺癌风险生物标志物的关联。
6. Time dependence of biomarkers: non-proportional effects of immunohistochemical panels predicting relapse risk in early breast cancer [O] . J Stephen, G Murray, D A Cameron, 2014

机译：生物标志物的时间依赖性：免疫组化专家小组预测早期乳腺癌复发风险的非比例效应
7. Time dependence of biomarkers: Non-proportional effects of immunohistochemical panels predicting relapse risk in early breast cancer [O] . Stephen, J., Murray, G., Cameron, D.A. (David), 2014

机译：生物标志物的时间依赖性：免疫组化指标的非比例效应预测早期乳腺癌的复发风险
8. Predicting Time-to-Relapse in Breast Cancer Using Neural Networks [R] . Buckley, J. D. 1997

机译：用神经网络预测乳腺癌复发时间

Time dependence of biomarkers: non-proportional effects of immunohistochemical panels predicting relapse risk in early breast cancer

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